Decoding Structure-Function Links in Early Atrophic Age-Related Macular Degeneration: Implications for Targeted Assessment and Management
Highlight
– Lesion size in early atrophic AMD correlates strongly with localized visual sensitivity impairment measured by fundus-controlled perimetry (FCP).
– The proximity of atrophic lesions to the fovea critically determines central visual acuity and reading performance.
– Functional assessments targeting lesions provide sensitive and domain-specific evaluation, complementing structural imaging.
– These findings support tailored FCP as an effective endpoint for monitoring disease progression and guiding interventions in early atrophic AMD.
Study Background
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