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Long-Term Safety and Ophthalmic Outcomes of Voretigene Neparvovec-rzyl in US Clinical Practice: Interim Multicenter Observational Findings
newschorioretinal atrophyretinal gene therapy

Long-Term Safety and Ophthalmic Outcomes of Voretigene Neparvovec-rzyl in US Clinical Practice: Interim Multicenter Observational Findings

By MedXY|Aug 18, 2026

Interim real-world data over nearly 4 years confirms the long-term safety and sustained visual benefits of voretigene neparvovec-rzyl in treating inherited retinal dystrophies, with manageable procedure-related adverse events including chor

Breakthrough Optogenetic Therapy UGX-201 Shows Promise for Advanced Retinitis Pigmentosa
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optogenetic therapy

Breakthrough Optogenetic Therapy UGX-201 Shows Promise for Advanced Retinitis Pigmentosa

By MedXY|Jul 2, 2026

An exploratory trial of UGX-201, a novel optogenetic therapy, demonstrated safety and meaningful visual improvements in patients with advanced nonsyndromic retinitis pigmentosa, including restoration of light perception in those previously

Most Patients Reach 20/40 After Cataract Surgery, but the Current MIPS Success Metric May Misclassify Quality and Exclude Nearly Half of Cases
newsCataract surgeryhealth equity

Most Patients Reach 20/40 After Cataract Surgery, but the Current MIPS Success Metric May Misclassify Quality and Exclude Nearly Half of Cases

By MedXY|May 9, 2026

A large multicenter study found that MIPS measure 191 captures high cataract surgery success rates but excludes many patients and may require case-mix adjustment to support fair surgeon comparisons.

Intravenous Alteplase Versus Oral Aspirin in Acute Central Retinal Artery Occlusion: Insights from the THEIA Phase 3 Trial and Contextual Evidence
OphthalmologyalteplaseAspirin

Intravenous Alteplase Versus Oral Aspirin in Acute Central Retinal Artery Occlusion: Insights from the THEIA Phase 3 Trial and Contextual Evidence

By MedXY|Oct 22, 2025

THEIA trial evaluated intravenous alteplase against oral aspirin in acute CRAO within 4.5 hours; no significant visual improvement difference was found, emphasizing the need for further research and meta-analyses to clarify thrombolysis ben

Oral Lamivudine: A Promising Alternative in the Management of Diabetic Macular Edema
Clinical UpdatesAnti-VEGFDiabetic Macular Edema

Oral Lamivudine: A Promising Alternative in the Management of Diabetic Macular Edema

By MedXY|Oct 8, 2025

A recent randomized, double-blind trial demonstrates that oral lamivudine significantly improves visual acuity in patients with center-involved diabetic macular edema, offering a cost-effective and safer alternative to conventional anti-VEG

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