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Advanced Right Ventricular Phenotyping Enhances Risk Stratification in Pulmonary Arterial Hypertension Follow-Up

MedXY Editorial Team•Aug 27, 2026•Cardiology
risk stratificationRight ventricular phenotypingechocardiographypulmonary arterial hypertension

Highlight

  • Echocardiography-derived right ventricular (RV) phenotypes identify distinct patterns of RV remodeling and dysfunction in pulmonary arterial hypertension (PAH) patients at first follow-up.
  • Four defined RV phenotypes correlate with mortality risk across ESC/ERS and REVEAL 2.0 risk categories, enhancing prognostic discrimination.
  • Severely dilated RV with poor RV-pulmonary arterial coupling (phenotype-4) predicts worse outcomes independently of established risk scores.
  • Mildly dilated RV with preserved coupling (phenotype-1) identifies better survival notably within intermediate risk groups, facilitating more personalized management.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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