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Unmasking Silent Heart Failure in Diabetes: Insights from the TARTAN-HF Trial

MedXY Editorial Team•Aug 21, 2026•Cardiology
diabetesHFpEFNatriuretic Peptidesheart failurescreening

Highlight

– Targeted screening using N-terminal pro-B-type natriuretic peptide (NT-proBNP) identifies a large proportion of previously unrecognized heart failure (HF) cases in high-risk diabetic patients.
– Most newly diagnosed HF cases in this population are heart failure with preserved ejection fraction (HFpEF).
– Screening led to increased use of sodium-glucose cotransporter 2 inhibitors (SGLT2i), disease-modifying therapy with established cardiovascular benefits.
– The number needed to screen was only five to detect one new HF case, highlighting the clinical impact and feasibility of such strategies.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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