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Adolescents who sustain mild traumatic brain injury (mTBI) face a significantly higher risk of developing mental health disorders over the subsequent year, influenced by factors such as sex, socioeconomic status, and prior psychiatric histo
An international Delphi panel concludes metabolic dysfunction‑associated steatotic liver disease (MASLD) raises colorectal cancer (CRC) risk. Experts call for earlier, risk‑adapted CRC screening and integrated metabolic care to reduce CRC b
An international expert consensus recommends practical principles and minimum requirements for general‑population screening for islet autoantibodies to detect early-stage type 1 diabetes, reduce DKA, enable early care and access to disease‑
This study validates the MD Anderson Dysphagia Inventory (MDADI) as a reliable screening tool for VFSS-graded swallowing impairment in head and neck cancer patients and proposes a concise four-item version to optimize clinical utility.
This study evaluates the independent association between incidental emphysema found on routine screening chest CT scans and all-cause mortality in a large Korean cohort, highlighting implications for risk stratification among ever-smokers.
The TARTAN-HF trial demonstrated that targeted natriuretic peptide screening in high-risk diabetic patients uncovers a high prevalence of undiagnosed heart failure, mainly HFpEF, enabling earlier treatment initiation and improved clinical c
This study evaluates four commercially available AI systems for diabetic retinopathy screening in Tanzania, demonstrating high sensitivity for referable and proliferative DR and highlighting considerations for implementation in low-resource
A machine learning model using electronic health records effectively identifies patients at high risk of atrial fibrillation, enabling targeted screening and early diagnosis to prevent stroke.
Emergency departments serve as vital venues for hepatitis C virus screening, particularly for persons experiencing homelessness who exhibit higher HCV prevalence and face healthcare access barriers. Evidence supports nontargeted screening i
This article critically appraises a multicenter study validating the Anti-BNLF2b antibody (P85-Ab) assay, highlighting its superior sensitivity and specificity for early nasopharyngeal carcinoma detection compared to established EBV-based b
The SUMMIT study reveals that respiratory symptoms are common among lung cancer screening participants and associated with increased lung cancer diagnosis risk within one year, challenging conventional asymptomatic screening definitions.
The Stockholm3 test combined with MRI screening significantly improves detection of clinically significant prostate cancer compared to PSA alone, reducing missed cases and unnecessary biopsies in a population-based study with 2-year follow-
A validation study suggests current liver fibrosis screening criteria are too broad. A refined risk-based approach reduced eligibility from 60–76% to 10–22% of adults while improving the yield of elevated liver stiffness and predicting futu
A large prospective study links smell disturbances to at least 139 conditions. Olfactory loss can be an early sign of neurological, ENT, metabolic, or systemic disease — and a practical, underused screening tool clinicians can adopt.
An international study developed AI-ECG models that diagnose and predict future moderate–severe mitral, tricuspid, and aortic regurgitation, validated across distinct populations and linked to subclinical chamber remodelling.
An AI-driven screening program (ATTRACTnet) applied to ECG, echocardiography, demographics and orthopedic history substantially increased case detection of transthyretin cardiac amyloidosis (ATTR‑CM) and led to rapid treatment initiation in
A 200‑patient cross‑sectional study found metformin use tripled the odds of vitamin B12 deficiency without affecting vitamins A, B1, B6, B9, C or E, highlighting the need for targeted B12 monitoring in long‑term metformin therapy.
A modeling study found that sequential population screening for familial hypercholesterolemia (FH) at ages 10 or 18 is clinically effective but not cost‑effective versus usual care, unless follow-up monitoring and lifestyle interventions fo
A 2023 population survey of 4,002 adults in the UK and US found that positive screens for avoidant/restrictive food intake disorder (ARFID) were common among people with disorders of gut–brain interaction (DGBI) and associated with greater
A concise synthesis of a 2025 multistakeholder Lancet workshop consensus on population and clinical strategies to prevent, detect, and manage alcohol‑associated liver disease.
