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Therapist-Guided e‑Health Cuts Fear of Cancer Recurrence in Colorectal Survivors: A Randomized Trial Shows Clinically Meaningful Benefits

MedXY Editorial Team•Nov 19, 2025•AI
colorectal cancere-health interventionfear of cancer recurrencerandomized trial

Highlights

– A therapist‑guided online intervention (TG‑iConquerFear) produced large, clinically meaningful reductions in overall fear of cancer recurrence (FCR) among colorectal cancer survivors with clinical FCR.
– At 3 months postintervention the between‑group difference in FCRI total score was 19.1 points (95% CI, 10.0–28.3; P < .001) with a standardized effect size (Cohen d) of 0.62.
– 81% of TG‑iConquerFear participants fell below the clinical FCR cutoff on the FCRI‑SF versus 43% with augmented self‑help (number needed to treat = 3).

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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