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Bridging the Gap in Emergency Care: The National Assessment of Pediatric Readiness in EMS

Bridging the Gap in Emergency Care: The National Assessment of Pediatric Readiness in EMS

The first national assessment of US EMS agencies reveals a critical need for improved pediatric readiness. While equipment scores are high, significant gaps exist in quality improvement and family-centered care, with Pediatric Emergency Car

Section: Emergency MedicineMar 14, 2026

Beyond Height Velocity: Longitudinal Impact of Long-Acting Growth Hormone on Body Mass Index in Pediatric Growth Hormone Deficiency

Beyond Height Velocity: Longitudinal Impact of Long-Acting Growth Hormone on Body Mass Index in Pediatric Growth Hormone Deficiency

This meta-analysis reveals that long-acting growth hormone (LAGH) is associated with a significant increase in BMI SD scores during the first year of treatment and upon switching from daily GH, suggesting a distinct metabolic profile compar

Section: Clinical UpdatesMar 12, 2026

Misaligned Urgency: Why Status Exceptions May Be Paradoxically Lowering Priority for the Sickest Children in Heart Transplantation

Misaligned Urgency: Why Status Exceptions May Be Paradoxically Lowering Priority for the Sickest Children in Heart Transplantation

A large-scale analysis of 6,026 pediatric heart transplant candidates reveals that status exceptions often prioritize patients with lower mortality risk than those meeting standard criteria, highlighting a significant misalignment in the U.

Section: CardiologyMar 10, 2026

Unorthodox JAK Inhibitor Dosing in Pediatric Moderate-to-Severe Alopecia Areata: A Comparative Evaluation of Tofacitinib and Baricitinib

Unorthodox JAK Inhibitor Dosing in Pediatric Moderate-to-Severe Alopecia Areata: A Comparative Evaluation of Tofacitinib and Baricitinib

This study of 100 pediatric patients with moderate-to-severe alopecia areata demonstrates that unorthodox dosing regimens of tofacitinib and baricitinib provide comparable efficacy and high tolerability over 24 weeks.

Section: DermatologyMar 5, 2026

Optimizing Pediatric Outcomes: Evidence-Based Advancements in Respiratory Delivery, Neonatal Support, and Precision Therapeutics

Optimizing Pediatric Outcomes: Evidence-Based Advancements in Respiratory Delivery, Neonatal Support, and Precision Therapeutics

This review synthesizes practice-changing pediatric research, highlighting how device selection in acute wheezing, automated oxygen titration in neonates, and novel siRNA therapies for hypercholesterolemia are redefining clinical standards

Section: Clinical UpdatesMar 2, 2026

Fractional Yellow Fever Vaccination Fails Non-Inferiority in Infants: Why Adult Data Cannot Be Extrapolated to Pediatric Populations

Fractional Yellow Fever Vaccination Fails Non-Inferiority in Infants: Why Adult Data Cannot Be Extrapolated to Pediatric Populations

A randomized, double-blind trial in Kenya and Uganda reveals that a 500 IU fractional dose of yellow fever vaccine is not non-inferior to the standard dose in infants, suggesting that lower dose requirements in adults are not generalizable

Section: Infectious DiseasesMar 2, 2026

Twice-Yearly Inclisiran Successfully Lowers LDL-C in Adolescents with Heterozygous Familial Hypercholesterolaemia: Insights from ORION-16

Twice-Yearly Inclisiran Successfully Lowers LDL-C in Adolescents with Heterozygous Familial Hypercholesterolaemia: Insights from ORION-16

The ORION-16 trial demonstrates that inclisiran, a twice-yearly siRNA therapy, significantly and safely reduces LDL cholesterol in adolescents with HeFH, offering a potent new tool for early cardiovascular risk management in high-risk pedia

Section: CardiologyFeb 25, 2026

Giving Kids a Voice: How Patient-Reported Outcome Measures are Transforming Pediatric Specialty Care

Giving Kids a Voice: How Patient-Reported Outcome Measures are Transforming Pediatric Specialty Care

Explore how standardized health questionnaires empower children and parents to share their priorities in medical settings, leading to more personalized and effective treatment plans.

Section: newsFeb 26, 2026

AAV9 Gene Therapy Shows Clinical Promise in Stabilizing Type II GM1 Gangliosidosis

AAV9 Gene Therapy Shows Clinical Promise in Stabilizing Type II GM1 Gangliosidosis

A Phase 1-2 trial of AAV9-GLB1 gene therapy in children with Type II GM1 gangliosidosis demonstrates significant biochemical improvements and stabilization of neurodevelopmental decline, marking a pivotal step toward treating this fatal lys

Section: NeurologyFeb 23, 2026

Beyond the Daily Pill: The Dawn of Long-Acting HIV Treatment for Adolescents

Beyond the Daily Pill: The Dawn of Long-Acting HIV Treatment for Adolescents

The IMPAACT 2017/MOCHA study reveals that long-acting injectable cabotegravir and rilpivirine administered every eight weeks is safe and highly effective for adolescents with HIV, potentially transforming the landscape of pediatric HIV care

Section: newsFeb 19, 2026

Why Environmental Interventions in Childcare May Not Be Enough: Insights from the NAPSACC UK Trial

Why Environmental Interventions in Childcare May Not Be Enough: Insights from the NAPSACC UK Trial

The NAPSACC UK cluster RCT found that a one-year environmental intervention in early childhood education settings did not significantly improve total energy consumption or physical activity, highlighting the need for broader policy-level ch

Section: newsFeb 17, 2026

Paracetamol vs. Ibuprofen in Infancy: The PIPPA Tamariki Trial Finds No Differential Risk for Eczema or Bronchiolitis

Paracetamol vs. Ibuprofen in Infancy: The PIPPA Tamariki Trial Finds No Differential Risk for Eczema or Bronchiolitis

The PIPPA Tamariki randomized controlled trial demonstrates that using paracetamol versus ibuprofen as needed in the first year of life does not significantly alter the risk of developing eczema or bronchiolitis by age one, challenging long

Section: Allergy & ImmunologyFeb 15, 2026

The Age Gap Penalty: Why Donor-Recipient Mismatch Shortens Graft Life in Adolescent Liver Transplants

The Age Gap Penalty: Why Donor-Recipient Mismatch Shortens Graft Life in Adolescent Liver Transplants

A nationwide study reveals that adolescent liver transplant recipients receiving grafts from donors 10+ years older face a 12.7% reduction in 10-year graft survival. Expanding allocation radii could improve access to age-matched organs and

Section: GastroenterologyFeb 11, 2026

Early Life Origins of Hypertension: Longitudinal Evidence That Blood Pressure Tracks from Birth to School Age

Early Life Origins of Hypertension: Longitudinal Evidence That Blood Pressure Tracks from Birth to School Age

A longitudinal study of the ENVIRONAGE cohort reveals that blood pressure tracks consistently from birth through childhood, with higher neonatal readings significantly increasing the risk of hypertension by age 11, emphasizing the need for

Section: CardiologyFeb 11, 2026

Mapping the Atopic Landscape: New Meta-Analysis Identifies Key Drivers and Critical Windows for Childhood Food Allergy

Mapping the Atopic Landscape: New Meta-Analysis Identifies Key Drivers and Critical Windows for Childhood Food Allergy

This comprehensive systematic review and meta-analysis of 190 studies involving 2.8 million participants establishes a 4.7% incidence rate for childhood food allergy and identifies early atopic conditions, microbiome disruptions, and delaye

Section: Allergy & ImmunologyFeb 10, 2026

Beyond the Count: How Product Factors and High Thresholds Shape Pediatric Platelet Transfusion Outcomes

Beyond the Count: How Product Factors and High Thresholds Shape Pediatric Platelet Transfusion Outcomes

A multicenter cohort study of 8,874 pediatric patients reveals that most prophylactic platelet transfusions occur above recommended thresholds. Factors such as pathogen reduction, additive solutions, and donor age significantly lower posttr

Section: Hematology-OncologyFeb 10, 2026

Over 50% of Publicly Insured Children Face Neurodevelopmental Disorders Following Infant Heart Surgery

Over 50% of Publicly Insured Children Face Neurodevelopmental Disorders Following Infant Heart Surgery

A comprehensive study highlights that over half of publicly insured children develop neurodevelopmental disorders within five years of infant cardiac surgery. While service utilization is high, a critical gap persists between initial screen

Section: CardiologyFeb 5, 2026

Combination Therapy Fails to Outperform Ibuprofen Alone for Pediatric Musculoskeletal Pain: Evidence from Two Randomized Controlled Trials

Combination Therapy Fails to Outperform Ibuprofen Alone for Pediatric Musculoskeletal Pain: Evidence from Two Randomized Controlled Trials

New clinical trials reveal that adding acetaminophen or hydromorphone to ibuprofen provides no additional pain relief for children with acute musculoskeletal injuries, while the addition of opioids significantly increases the risk of advers

Section: Emergency MedicineJan 25, 2026

Digital Storytelling Boosts Pediatric Influenza Vaccination Rates Despite Low Engagement: Insights from a Pilot Randomized Trial

Digital Storytelling Boosts Pediatric Influenza Vaccination Rates Despite Low Engagement: Insights from a Pilot Randomized Trial

A pilot randomized clinical trial reveals that text-based digital stories centered on community voices significantly improved influenza vaccination rates among children in Black communities, even though only 7% of caregivers viewed the narr

Section: newsJan 17, 2026

Targeted Bone Support: High-Dose Vitamin D and Calcium Improve Bone Mineral Density in Adolescents with HIV and Baseline Insufficiency

Targeted Bone Support: High-Dose Vitamin D and Calcium Improve Bone Mineral Density in Adolescents with HIV and Baseline Insufficiency

The VITALITY trial reveals that while high-dose vitamin D and calcium supplementation did not benefit all adolescents with HIV, it significantly improved bone density in those with baseline vitamin D insufficiency, providing a safe strategy

Section: newsJan 14, 2026

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