microbiome

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Bridging Periodontitis and Clonal Hematopoiesis: Implications for Solid Tumor Metastasis, Clinical Trial Design, and Microbiome Dynamics

This review synthesizes evidence linking periodontitis-induced inflammation with clonal hematopoiesis, exploring implications for tumor metastasis, trial methodology, and microbiome-host crosstalk.

Section: Clinical UpdatesJul 24, 2026

PRO-PLATINUM Trial: Probiotic Modulation of the Microbiome to Enhance Outcomes in Ovarian Cancer Chemotherapy

The PRO-PLATINUM trial evaluates a novel 5-strain probiotic’s effect on gut and vaginal microbiome composition and clinical outcomes in ovarian cancer patients undergoing platinum chemotherapy, assessing safety, feasibility, and translation

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Bridging Periodontitis and Clonal Hematopoiesis: Implications for Solid Tumor Metastasis, Clinical Trial Design, and Microbiome Dynamics

PRO-PLATINUM Trial: Probiotic Modulation of the Microbiome to Enhance Outcomes in Ovarian Cancer Chemotherapy

Quorum-Sensing Molecules Elevated in Long-Standing Ulcerative Colitis May Help Drive Colitis-Associated Cancer

The Gut-Liver Axis Unveiled: How Microbiome Signatures Track Disease Progression from Fatty Liver to Cancer

The Unfinished Agenda in Helicobacter pylori Treatment: Resistance, Microbiome Effects, and Future Directions

Enterococcus faecalis Drives MHC-II Expression in Intestinal Epithelium: A Novel Mechanism Linking Gut Microbiome Dysbiosis to Lethal Graft-versus-Host Disease

Dietary Lipid Sequestration and Metabolic Rewiring in Colorectal Cancer: New Mechanistic Frontiers and Therapeutic Potential

Mapping the Atopic Landscape: New Meta-Analysis Identifies Key Drivers and Critical Windows for Childhood Food Allergy

Antibiotic Exposure Linked to Shorter Biologic Survival in Psoriasis: A Large French Cohort Suggests a Dose–Response Relationship

Microbiota, 3‑Hydroxyanthranilic Acid and Dopaminergic Signalling: A New Pathway Linking Obesity to Attention Deficits

Evaluating the Necessity of Live Microbes in Fecal Microbiota Transplantation for C. difficile Recurrence: Insights from a Non-Inferiority Trial

Decoding the Role of Reflux Secondary Bile Acids in Barrett’s Esophagus: Microbiome and Transcriptome Insights

The Gut’s Sixth Sense: How Your Microbiome Quietly Controls Appetite

Exploring the Gut Microbiota-Insomnia Connection: Evidence and Controversies

Metformin and ‘Anti‑Aging’: Promising Mechanisms but Mixed Clinical Evidence — What Recent Trials Tell Us

Your Gut, Your Mood: How the ‘Second Brain’ Can Beat the Blues

Gut Feeling: The Surprising Link Between Your Stomach and Your Mood