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Gestational Diabetes

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OB/GYN & Women's Health

Oral Antihyperglycemic Agents Versus Insulin for Gestational Diabetes Mellitus: Societal Cost-Effectiveness Analysis of the SUGAR-DIP Randomized Controlled Trial

This study evaluates the societal cost-effectiveness of oral antihyperglycemic agents compared to insulin for gestational diabetes treatment, showing oral agents offer comparable benefits at potentially lower costs with small quality-adjust

Nov 2, 2026
Clinical Updates

Low-Carbohydrate Diets, Nutritional Adequacy, Glycemia, and Perinatal Outcomes in Women With Gestational Diabetes Mellitus: Insights from the DiGest Trial and Contemporary Evidence

This review synthesizes current evidence on low-carbohydrate diets in gestational diabetes mellitus (GDM), highlighting effects on glycemia, nutrient adequacy, and perinatal outcomes from the DiGest trial and supporting literature.

Oct 28, 2026
Clinical Updates

In Utero Exposure to Maternal Diabetes and Its Impact on Offspring Diabetes Risk among First Nations and Non-First Nations Populations: A Comprehensive Review

This review synthesizes evidence linking in utero exposure to preexisting and gestational diabetes with increased diabetes incidence in offspring, highlighting stronger effects among First Nations populations and the mitigating role of peri

Oct 5, 2026
Diabetes & Endocrinology

Social Inequalities in Gestational Diabetes: Insights from a Nationwide Swedish Cohort Study

This Swedish cohort study reveals growing gestational diabetes prevalence with marked disparities by social determinants such as education, income, and nativity, underscoring the need for targeted prevention and equitable care.

Sep 16, 2026Sign in to read
Diabetes & Endocrinology

Gestational Diabetes Mellitus: Insights from 25 Years of Research on Early Risk, Prevention, and Long-Term Outcomes

A 25-year synthesis of research on gestational diabetes mellitus revealing early metabolic alterations, prevention strategies, optimized treatments, and lifelong consequences for mothers and offspring.

Sep 4, 2026
Diabetes & Endocrinology

Impact of Third-Trimester Energy Restriction on Postnatal Maternal and Infant Body Composition After Gestational Diabetes: Insights from the DiGest Follow-up Study

Third-trimester energy restriction in women with gestational diabetes and elevated BMI does not adversely affect infant growth or body composition through the first postnatal year, suggesting safety of modest maternal weight loss in late pr

Aug 27, 2026Sign in to read
Diabetes & Endocrinology

Gestational Diabetes Mellitus: Ethnic Variations in Recurrence and Long-Term Type 2 Diabetes Risk

This study highlights the high recurrence of gestational diabetes mellitus (GDM) and its strong association with future type 2 diabetes, particularly among Asian women, underscoring the need for ethnicity-specific prevention and screening s

Aug 22, 2026
Diabetes & Endocrinology

Impact of Semaglutide Exposure on Gestational Weight Gain and Pregnancy Outcomes in Overweight and Obese Women

This study investigates how semaglutide exposure before and during pregnancy affects gestational weight gain and key pregnancy outcomes in women with overweight or obesity, highlighting increased risks that may stem from treatment discontin

Aug 14, 2026
Diabetes & Endocrinology

Leveraging Polygenic Scores to Predict Diabetes Risk After Gestational Diabetes: Insights from a 30-Year Cohort Study

Polygenic scores can predict type 1 diabetes risk after gestational diabetes, especially when combined with clinical factors, but show limited utility for type 2 diabetes prediction.

Aug 5, 2026Sign in to read
Diabetes & Endocrinology

The Economic Burden of Gestational Diabetes and Body Mass Index Changes Between Pregnancies: A Retrospective Cohort Study

This study examines how gestational diabetes and BMI changes between pregnancies impact hospital stay length and birthing costs, highlighting the importance of preventive care.

Jul 23, 2026Sign in to read
Clinical Updates

Evaluation of Postpartum Glucose Tolerance Test Results Based on Criteria and Timing: Implications for Diagnostic Accuracy and Clinical Practice

Reviewing ADA 2022 vs ACOG criteria and timing effects on postpartum OGTT in GDM women reveals inpatient testing increases screening uptake but varies in diabetes classification; highlights the need for consensus on test timing and interpre

Jul 8, 2026
Diabetes & Endocrinology

Gestational Diabetes and Later Cancer Risk: Reassuring Overall Results, but a Kidney Cancer Signal Emerges

A Danish registry study found no overall increase in selected cancers after gestational diabetes, but did observe a small absolute and relative increase in kidney cancer risk.

Jun 17, 2026
Diabetes & Endocrinology

Prepregnancy Insulin Resistance and Fertility Outcomes in Women With PCOS

Higher insulin resistance before pregnancy was linked to poorer ovulation, lower pregnancy and live-birth rates, and more gestational diabetes in women with PCOS. Improving insulin resistance during treatment was associated with better preg

May 26, 2026
Diabetes & Endocrinology

Higher PFAS Exposure During Pregnancy Was Not Linked to Increased Gestational Diabetes in the ECHO Cohort

In a pooled U.S. pregnancy cohort, maternal PFAS concentrations were not associated with a higher prevalence of gestational diabetes, and fasting glucose findings were largely null.

May 6, 2026
Diabetes & Endocrinology

Gut Microbiome Signatures May Help Explain Why Gestational Diabetes Raises Later Type 2 Diabetes Risk in Hispanic/Latina Women

In HCHS/SOL, prior gestational diabetes was linked to a proinflammatory gut microbiome, adverse metabolite patterns, and higher future type 2 diabetes risk, suggesting a plausible microbiome-mediated pathway after pregnancy.

May 3, 2026
Diabetes & Endocrinology

Maternal Diabetes and Early Neurodevelopment: Differential Risks Emerge Across Diabetes Types and Infant Sex

A nationwide cohort study of 466,462 infants reveals that maternal pregestational diabetes significantly increases the risk of delayed developmental milestones, with type 1 diabetes conferring the highest risk and female offspring showing p

Apr 17, 2026
Diabetes & Endocrinology

Flash Glucose Monitoring Fails to Improve Glycemic Control but Reduces Large-for-Gestational-Age Risk in Gestational Diabetes

A randomized trial of 205 pregnant women with gestational diabetes found that adjunctive flash glucose monitoring did not improve time-in-range glucose measurements compared to standard self-monitoring. However, the device was associated wi

Apr 9, 2026Sign in to read
Diabetes & Endocrinology

Inpatient Postpartum Glucose Testing Triples Completion Rates After Gestational Diabetes

A randomized controlled trial demonstrates that performing oral glucose tolerance tests before hospital discharge significantly improves screening rates and patient satisfaction compared to standard outpatient care for women with gestationa

Mar 30, 2026
Clinical Updates

Precision Medicine in Gestational Diabetes: Decoding Heterogeneity Through Data-Driven Phenotypic Clustering and Risk Stratification

This review analyzes a landmark machine learning study identifying four distinct GDM phenotypic clusters, revealing that early-diagnosed, comorbidity-related GDM carries a four-fold higher risk of postpartum diabetes.

Mar 26, 2026
Diabetes & Endocrinology

Beyond a Uniform Approach: Data-Driven Phenotyping Reveals High-Risk Clusters in Gestational Diabetes Mellitus

A groundbreaking machine learning study of over 37,000 patients identifies four distinct GDM phenotypic clusters. These findings demonstrate that early-diagnosed, high-comorbidity phenotypes carry a four-fold increased risk of postpartum di

Mar 22, 2026
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