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Widening the Spectrum of Disease Expression due to Heterozygous Variants in EFEMP1
newscase reportdiagnosis

Widening the Spectrum of Disease Expression due to Heterozygous Variants in EFEMP1

By MedXY|Sep 13, 2026

A case series delineating a novel EFEMP1 variant, p.Arg140Trp, associated with late-onset peripheral retinal degeneration distinct from classic DHRD/ML, highlighting rod dysfunction precedes structural changes.

Approach to the Patient: Theranostics as Precision Medicine for Neuroendocrine Tumors
Diabetes & Endocrinologyneuroendocrine tumorstheranostics

Approach to the Patient: Theranostics as Precision Medicine for Neuroendocrine Tumors

By MedXY|Sep 5, 2026

Presentation of three neuroendocrine tumor cases illustrating theranostics integration in diagnosis, treatment, and management, highlighting receptor-based imaging and personalized radionuclide therapy.

A patient with CHILD syndrome mimicking Hailey-Hailey disease: A diagnostic challenge
Dermatologycase reporttreatment

A patient with CHILD syndrome mimicking Hailey-Hailey disease: A diagnostic challenge

By MedXY|Sep 3, 2026

We present a molecularly confirmed case of CHILD syndrome mimicking Hailey-Hailey disease without classical features, highlighting diagnostic pitfalls and benefits of targeted therapy.

A Split-Muscle Support Technique for Direct-To-Implant Breast Reconstruction: A Case Series
newsBreast Reconstructionimplant technique

A Split-Muscle Support Technique for Direct-To-Implant Breast Reconstruction: A Case Series

By MedXY|Sep 2, 2026

This report details the first application of the split-muscle support technique in direct-to-implant breast reconstruction, highlighting its approach to reduce animation deformity and enhance implant support with less ADM use.

Variable Effects of Vagus Nerve Stimulator Cycling on Vocal Fold Motion: A Videographic Case Series
Neurologydysphoniavocal fold motion

Variable Effects of Vagus Nerve Stimulator Cycling on Vocal Fold Motion: A Videographic Case Series

By MedXY|Aug 31, 2026

This case series examines eight patients experiencing dysphonia after vagus nerve stimulator placement, highlighting variable and transient vocal fold motion changes during device cycling.

Head Trauma-Induced Superior Semicircular Canal Dehiscence Syndrome: A Case Series and Review
newsotologyaudiovestibular testing

Head Trauma-Induced Superior Semicircular Canal Dehiscence Syndrome: A Case Series and Review

By MedXY|Aug 28, 2026

A case series highlighting how minor head trauma can precipitate clinically significant superior semicircular canal dehiscence syndrome in predisposed individuals, detailing audiovestibular findings and diagnostic considerations.

Individualized vs Standard Blood Pressure Control During Mechanical Thrombectomy for Acute Ischemic Stroke: Insights from the DETERMINE Randomized Clinical Trial
Critical Caremechanical thrombectomycase report

Individualized vs Standard Blood Pressure Control During Mechanical Thrombectomy for Acute Ischemic Stroke: Insights from the DETERMINE Randomized Clinical Trial

By MedXY|Aug 24, 2026

A randomized clinical trial comparing individualized versus standard blood pressure control during mechanical thrombectomy for ischemic stroke showed no significant difference in 90-day functional outcomes or safety.

Ultra-Long-Distance Robotic-Assisted Subretinal Injection for Submacular Hemorrhage: A Case Report
newssubmacular hemorrhagetelemedicine

Ultra-Long-Distance Robotic-Assisted Subretinal Injection for Submacular Hemorrhage: A Case Report

By MedXY|Aug 23, 2026

This report describes the successful ultra-long-distance robotic-assisted subretinal injection of recombinant tissue plasminogen activator for submacular hemorrhage, demonstrating procedural feasibility and safety across 4000 km.

Does Industry Influence Persist? Financial Conflicts and ADM Outcomes After the 2021 FDA Safety Alert: A Case Report Analysis
newsBreast Reconstructionacellular dermal matrix

Does Industry Influence Persist? Financial Conflicts and ADM Outcomes After the 2021 FDA Safety Alert: A Case Report Analysis

By MedXY|Aug 20, 2026

This report examines the ongoing association between industry payments and positive outcomes reported in acellular dermal matrix (ADM) studies following the 2021 FDA safety alert.

Congenital Tuberculosis in a 2-Week-Old Neonate With an Asymptomatic Mother
Infectious Diseasestuberculosisneonatal infectious disease

Congenital Tuberculosis in a 2-Week-Old Neonate With an Asymptomatic Mother

By MedXY|Aug 20, 2026

A 2-week-old neonate developed congenital tuberculosis despite an asymptomatic mother, illustrating diagnostic challenges and the need for heightened awareness of TB in pregnancy.

Low-dose Blinatumomab Therapy in Multidrug-Resistant Rheumatoid Arthritis: A Case Series Analysis
Hematology-OncologyT-cell Engagermultidrug resistance

Low-dose Blinatumomab Therapy in Multidrug-Resistant Rheumatoid Arthritis: A Case Series Analysis

By MedXY|Aug 17, 2026

A case series assessing the safety and efficacy of low-dose blinatumomab in 15 patients with multidrug-resistant rheumatoid arthritis showed synovial B-cell depletion, reduced disease activity, and improved response to previously ineffectiv

Extra-Endocrine Features in Infancy as Early Clues to Multiple Endocrine Neoplasia Type 2B: A Case Series from Bambino Gesù Children’s Hospital
Diabetes & Endocrinologycase reporttreatment

Extra-Endocrine Features in Infancy as Early Clues to Multiple Endocrine Neoplasia Type 2B: A Case Series from Bambino Gesù Children’s Hospital

By MedXY|Aug 14, 2026

We report five pediatric MEN2B cases highlighting early extra-endocrine signs such as persistent constipation and alacrimia, enabling prompt genetic diagnosis and thyroidectomy before medullary thyroid carcinoma progression.

Ersodetug for Refractory Hypoglycemia Due to Malignant Insulin-Secreting Tumors: A Compassionate Use Case Series
Diabetes & Endocrinologyhyperinsulinisminsulin receptor antibody

Ersodetug for Refractory Hypoglycemia Due to Malignant Insulin-Secreting Tumors: A Compassionate Use Case Series

By MedXY|Aug 8, 2026

This case series describes compassionate use of ersodetug in eight adults with refractory hypoglycemia from malignant insulin-secreting tumors, demonstrating improved glycemic control, reduced hypoglycemia, and enhanced functional status.

Midbrain Lesion Bridges Akinetic and Cerebellar Mutism: A Case Report
Neurologymidbraincase report

Midbrain Lesion Bridges Akinetic and Cerebellar Mutism: A Case Report

By MedXY|Jul 28, 2026

A 10-year-old with a midbrain ischemic lesion after craniopharyngioma resection developed mutism with features of both akinetic mutism and cerebellar mutism, suggesting a shared neurocircuitry that responded to methylphenidate.

Fungal Endophthalmitis Associated with Contaminated Trypan Blue in Cataract Surgery: A Retrospective Case Series
Infectious Diseasescase reportCataract surgery

Fungal Endophthalmitis Associated with Contaminated Trypan Blue in Cataract Surgery: A Retrospective Case Series

By MedXY|Jul 24, 2026

Six cases of postoperative fungal endophthalmitis caused by Sarocladium kiliense following cataract surgery involving contaminated trypan blue are reported, highlighting diagnosis, management, and outcomes.

Health Insurance Instability Following Firearm Injury: A Matched Cohort Case Report
Critical Carecase reportclinical outcomes

Health Insurance Instability Following Firearm Injury: A Matched Cohort Case Report

By MedXY|Jul 20, 2026

This report highlights the increased risk of health insurance instability in survivors of firearm injury, emphasizing the challenges to continuous care and financial burden post-injury.

Outcomes of Nasal Vertical Rectus Belly Transposition and Lateral Rectus Recession for Large Exotropia after Medial Rectus Transection: A Case Series
newscase reportexotropia

Outcomes of Nasal Vertical Rectus Belly Transposition and Lateral Rectus Recession for Large Exotropia after Medial Rectus Transection: A Case Series

By MedXY|Jul 17, 2026

This report describes outcomes of nasal vertical rectus belly transposition and lateral rectus recession to treat large-angle exotropia secondary to medial rectus transection in 14 patients, highlighting better results after endoscopic sinu

Artificial Intelligence Smart Eyeglasses for the Detection and Description of Stationary Objects: A Pilot Feasibility Study
AIartificial intelligencecase report

Artificial Intelligence Smart Eyeglasses for the Detection and Description of Stationary Objects: A Pilot Feasibility Study

By MedXY|Jul 15, 2026

A pilot study evaluating Ray-Ban Meta AI eyeglasses demonstrated high accuracy in single object identification and moderate performance in descriptive tasks, suggesting promise for aiding individuals with low vision.

Clinical Diagnosis of Calcium Release Deficiency Syndrome in a Family With Sudden Cardiac Death
Cardiologyarrhythmia diagnosiscalcium release deficiency syndrome

Clinical Diagnosis of Calcium Release Deficiency Syndrome in a Family With Sudden Cardiac Death

By MedXY|Jul 10, 2026

A 5-generation French Canadian family with history of sudden cardiac death was diagnosed with calcium release deficiency syndrome using a novel burst pacing provocation test, illustrating its clinical utility and highlighting the importance

Blood Pressure Assessment in Ophthalmology Clinics for Patients With Diabetes: A Case Series Analysis
Diabetes & Endocrinologyblood pressure assessmentcase report

Blood Pressure Assessment in Ophthalmology Clinics for Patients With Diabetes: A Case Series Analysis

By MedXY|Jul 9, 2026

This case series reveals a high prevalence of uncontrolled hypertension among diabetic patients visiting ophthalmology clinics and highlights the importance of in-clinic blood pressure screening to identify and manage cardiovascular risk.

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