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Diabetes & Endocrinology

Unraveling the Complex Interplay of BMI and Inflammation on Assisted Reproductive Outcomes in PCOS Women

This study reveals bidirectional mediation between BMI and inflammatory markers affecting embryo quality and availability in PCOS women undergoing ART, highlighting BMI’s predominant role.

Oct 26, 2026
General Surgery

Elevated BMI and Open Airway Reconstruction: Disentangling the Impact on Postoperative Outcomes

This study demonstrates that elevated BMI and obesity classification do not increase the risk of complications or prolong recovery times following open airway reconstruction surgeries, guiding surgical decision-making in overweight and obes

Oct 8, 2026
Diabetes & Endocrinology

Harmonizing Estradiol Reference Ranges in Postmenopausal Women: A Breakthrough for Accurate Hormone Assessment and Risk Prediction

This article reviews the establishment of international standardized reference ranges for plasma estradiol in postmenopausal women, highlighting the influence of BMI and assay harmonization using CDC standards, with implications for therapy

Sep 20, 2026
news

Tailoring Misoprostol Dosing for Labor Induction: The Influence of BMI and Administration Route

Obesity increases the number of misoprostol doses needed for active labor during induction, with buccal dosing requiring more doses than vaginal, highlighting implications for individualized labor management.

Aug 24, 2026
Diabetes & Endocrinology

Steroids, Stress, and Body Mass Index Interact to Accelerate Female Pubertal Development

Elevated glucocorticoids, androgens, and progesterone metabolites, combined with high BMI and stress, accelerate the onset of puberty in girls, particularly breast development (thelarche).

Aug 19, 2026
Cardiology

Beyond BMI: How Waist Circumference and Waist-to-Hip Ratio Enhance Cardiovascular Risk Prediction

This analysis reveals that waist circumference and waist-to-hip ratio improve cardiovascular risk classification beyond BMI, identifying individuals with hidden risk and refining prognostic assessments across multiple cardiovascular outcome

Aug 13, 2026
Gastroenterology

New Obesity Definitions Reclassify Many MASLD Patients but Do Not Improve Liver Risk Prediction

New obesity definitions reclassify many MASLD patients as obese but do not improve prediction of liver-related events over BMI alone, according to a multinational cohort study.

Jul 29, 2026Sign in to read
Cardiology

Oral Semaglutide and Cardiovascular Benefits in the SOUL Trial: Impact of Baseline and Changes in HbA1c and BMI on Clinical Outcomes

This analysis of the SOUL trial shows oral semaglutide reduces major cardiovascular events, with greater benefits linked to higher baseline HbA1c and larger HbA1c reductions, while BMI changes did not significantly affect outcomes.

Jul 22, 2026
news

Body Mass Index and Nutritional Status With Immunotherapy Response in Head and Neck Cancer

In advanced head and neck squamous cell carcinoma, pretreatment weight loss and low prognostic nutritional index were linked to shorter progression-free survival after immunotherapy, while baseline BMI was not predictive.

May 20, 2026
Clinical Updates

Beyond Height Velocity: Longitudinal Impact of Long-Acting Growth Hormone on Body Mass Index in Pediatric Growth Hormone Deficiency

This meta-analysis reveals that long-acting growth hormone (LAGH) is associated with a significant increase in BMI SD scores during the first year of treatment and upon switching from daily GH, suggesting a distinct metabolic profile compar

Mar 11, 2026
Clinical Updates

Causal Insights Into Hidradenitis Suppurativa: Mendelian Randomization Evidence Linking BMI, Inflammatory Bowel Disease, and Smoking

Recent Mendelian randomization analyses demonstrate causal effects of increased BMI and inflammatory bowel disease on hidradenitis suppurativa risk, elucidating modifiable contributions beyond genetic correlations with psoriasis and systemi

Dec 24, 2025Sign in to read
Cardiology

Underweight in Type 2 Diabetes Raises Cardiovascular Risk — Severe Leanness Carries Greater Risk Than Obesity

A nationwide Korean cohort found that underweight patients with Type 2 diabetes—especially those with severe underweight—have higher cardiovascular risk than normal-weight and even some obese patients, underscoring the need to screen and ma

Dec 2, 2025
news

T2 Mapping Detects BMI-Linked Cartilage Changes and Lateral Compartment Signal Differences in Population-Based Knee OA

In a large population-based sample, cartilage T2 relaxation times correlated with BMI and were higher in knees with MRI-defined osteoarthritis, particularly in lateral cartilage subregions; T2 did not reflect patient-reported symptoms.

Nov 2, 2025Sign in to read
news

Partitioning Knee Osteoarthritis Genetic Risk by BMI Association Clarifies Prediction and Mechanisms

Partitioning a knee osteoarthritis polygenic score into BMI-associated and BMI-independent components clarifies genetic contributions, improves interpretability, and offers a path to tailored prediction and prevention.

Nov 2, 2025
Diabetes & Endocrinology

Revisiting Obesity Classification: Insights from a Population-Based Survey in Peru Using New Clinical Frameworks

This review examines a landmark Peruvian study applying new obesity definitions that incorporate clinical dysfunction and adiposity measures beyond BMI, revealing substantial underdiagnosis with traditional approaches and ethnic variation i

Oct 19, 2025
Diabetes & Endocrinology

Once-Weekly Semaglutide 2.4 mg for Obesity Management in Asian Adults: Efficacy, Safety, and Policy Insights from the STEP 11 Trial

The STEP 11 trial demonstrates that once-weekly semaglutide 2.4 mg significantly reduces bodyweight in Asian adults with obesity (BMI ≥25 kg/m²), supporting its safety and guideline inclusion in these populations with unique BMI thresholds.

Sep 7, 2025
Cardiology

Tirzepatide’s Role in Obesity-Related HFpEF: Influence of BMI, Central Adiposity, and Weight Loss from the SUMMIT Trial

Tirzepatide reduces heart failure risk in obese HFpEF patients regardless of BMI or central adiposity, with greater benefits on exercise capacity and symptom scores associated with higher BMI and weight loss.

Aug 17, 2025

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