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Multidose Ibuprofen Significantly Alleviates Pain During Intrauterine Device Insertion: Insights from the MIPI Trial

MedXY Editorial Team•Aug 18, 2026•news
pain managementibuprofenintrauterine devicerandomized controlled trial

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The Multidose Ibuprofen Prior to Intrauterine device insertion (MIPI) trial provides high-level evidence supporting a preemptive, multidose regimen of ibuprofen to reduce pain during IUD insertion. The trial found significant and clinically meaningful reductions in pain intensity during the procedure compared to placebo. However, no significant differences were observed in pain 24 hours postinsertion or in additional analgesic usage.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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