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IgG4-Related Disease Shows No Increased Risk of Malignancy: Insights from a Large Cohort Study

MedXY Editorial Team•Oct 15, 2026•news
Autoimmune diseasebệnh liên quan đến IgG4epidemiologyLymphomamalignancy

Highlight

  • IgG4-related disease (IgG4-RD) is not associated with an increased incidence of malignancy compared to the general U.S. population.
  • Among IgG4-RD patients, smoking and older age at disease onset are significant risk factors for developing malignancy.
  • Female sex and submandibular gland involvement in IgG4-RD are associated with a decreased risk of malignancy.
  • The most common malignancies in this IgG4-RD cohort included lymphoma, prostate, and lung cancers.

Study Background

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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