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MedXY AI/MedXY News/Tag: Autoimmune disease
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Phenotype-Specific Mosaic Chromosomal Alterations in Systemic Sclerosis: Implications for Disease Subtypes and Clinical Outcomes
Hematology-Oncologymosaic chromosomal alterationssystemic sclerosis

Phenotype-Specific Mosaic Chromosomal Alterations in Systemic Sclerosis: Implications for Disease Subtypes and Clinical Outcomes

By MedXY|Oct 17, 2026

This article explores the differential associations of mosaic chromosomal alterations (mCAs), especially chromosomal loss and mosaic loss of the X chromosome, with systemic sclerosis and its subtypes, revealing phenotype-specific genetic co

IgG4-Related Disease Shows No Increased Risk of Malignancy: Insights from a Large Cohort Study
newsAutoimmune disease
bệnh liên quan đến IgG4

IgG4-Related Disease Shows No Increased Risk of Malignancy: Insights from a Large Cohort Study

By MedXY|Oct 15, 2026

A large single-center cohort study found no increased incidence of malignancy in patients with IgG4-related disease (IgG4-RD). Smoking and older age increased malignancy risk, while female sex and submandibular gland involvement were protec

Why Metrics Matter in Thyroid Eye Disease: Exploring the Innovate TED Initiative
Diabetes & EndocrinologyClinical MetricsInnovate TED Initiative

Why Metrics Matter in Thyroid Eye Disease: Exploring the Innovate TED Initiative

By MedXY|Sep 13, 2026

This article examines the critical need for refined clinical metrics in thyroid eye disease (TED) to better evaluate new targeted therapies, highlighting the Innovate TED Initiative’s efforts to develop and validate comprehensive outcome me

Assessing the Risk of CNS Demyelination Associated with TNF-α Inhibitors: Insights from a Large US Health Network
NeurologyAutoimmune diseaseCNS demyelination

Assessing the Risk of CNS Demyelination Associated with TNF-α Inhibitors: Insights from a Large US Health Network

By MedXY|Jul 20, 2026

A large retrospective study reveals a small but significant increase in CNS demyelination risk among patients treated with TNF-α inhibitors, varying by agent, with generally low absolute incidence.

Engineering a Cure: How CAR T-Cell Therapy is Transforming the Fight Against Autoimmune Hemolytic Anemia
Allergy & ImmunologyAutoimmune diseasebệnh huyết học

Engineering a Cure: How CAR T-Cell Therapy is Transforming the Fight Against Autoimmune Hemolytic Anemia

By MedXY|Jan 14, 2026

A groundbreaking study shows that CD19 CAR T-cell therapy can induce sustained, drug-free remission in patients with severe, multirefractory autoimmune hemolytic anemia by successfully eliminating the autoreactive B-cells that drive the dis

Guardians Within: Unveiling the Nobel-Winning Discovery of Regulatory T Cells and Their Crucial Role in Immune Balance
newsAutoimmune diseaseFoxp3

Guardians Within: Unveiling the Nobel-Winning Discovery of Regulatory T Cells and Their Crucial Role in Immune Balance

By MedXY|Oct 6, 2025

The 2025 Nobel Prize honors the groundbreaking discovery of regulatory T cells (Tregs), key immune modulators that maintain tolerance and prevent autoimmunity, inspiring new therapies for autoimmune disease, transplantation, and cancer.

Guardians Within: The Nobel-Winning Discovery of Regulatory T Cells and Their Role in Immune Balance
Allergy & ImmunologyAutoimmune diseaseFoxp3

Guardians Within: The Nobel-Winning Discovery of Regulatory T Cells and Their Role in Immune Balance

By MedXY|Oct 6, 2025

The 2025 Nobel Prize in Physiology or Medicine honors groundbreaking work on regulatory T cells, revealing how the immune system avoids self-attack while combating threats, paving the way for novel therapies in autoimmune and transplant med

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