Enhancing Diagnostic Accuracy in Stable Coronary Artery Disease: Impact of Adding CT-derived Fractional Flow Reserve (FFRct) – Insights from the FUSION Trial
Computed tomographyinvasive coronary angiographyDiagnostic PathwayStable Coronary Artery DiseaseFractional Flow Reserve
Highlight
- Adding CT-derived fractional flow reserve (FFRct) to the diagnostic pathway significantly reduces the rate of invasive coronary angiography (ICA) without obstructive coronary artery disease (CAD) in patients with intermediate (50-90%) stenosis on CCTA.
- The overall number of ICAs performed was lower with FFRct guidance at both 90 days and 1 year, reflecting better patient selection for invasive procedures.
- Revascularization rates, major adverse cardiac events (MACE), quality of life, and healthcare costs were comparable between FFRct-guided and usual care groups, with low event rates in both arms.
Study Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.