We use cookies

Our website uses essential cookies and, with your consent, additional cookies to measure performance and improve our services. Cookie Policy.

You can change your choice at any time.

MMedXYNews
HomeVideos
© 2026 MedXY
Contact usAbout usPrivacy PolicyMedXY story
MedXY AI/MedXY News/Tag: Tumor Microenvironment
MedXY News
EnglishTag

Tumor Microenvironment

Ask MedXY AI
type 2 diabetesclinical trialheart failureimmunotherapyobesitycardiovascular riskatrial fibrillationbiomarkerscritical careclinical trialsHypertensionartificial intelligenceCardiologyoncologypublic healthtype 1 diabetesdiabetesMortalityAlzheimer's diseasecardiovascular diseasebreast cancerepidemiology

Latest news

Tag

Unveiling the Molecular Evolution from Primary Gastric Cancer to Peritoneal Metastases: Implications for Targeted Surgical Oncology
General SurgeryTumor MicroenvironmentPeritoneal metastases

Unveiling the Molecular Evolution from Primary Gastric Cancer to Peritoneal Metastases: Implications for Targeted Surgical Oncology

By MedXY|Sep 5, 2026

This study elucidates transcriptomic differences between primary gastric cancers and peritoneal metastases, revealing distinct tumor microenvironments and molecular pathways, highlighting potential targets for improved diagnosis and therapy

Distinct Myeloid Landscapes Define Prognostic Niches in Extranodal NK/T-Cell Lymphoma
Hematology-OncologyMyeloid heterogeneity
Tumor Microenvironment

Distinct Myeloid Landscapes Define Prognostic Niches in Extranodal NK/T-Cell Lymphoma

By MedXY|Aug 30, 2026

Spatial multimodal profiling reveals two macrophage-defined ENKTL subgroups with distinct tumor-myeloid interactions influencing prognosis and potential immunotherapy targets.

Breast Implant-Associated Anaplastic Large Cell Lymphoma: Insights into Cellular Diversity, Immune Suppression, and Therapeutic Opportunities
Hematology-Oncologyimmune suppressionTumor Microenvironment

Breast Implant-Associated Anaplastic Large Cell Lymphoma: Insights into Cellular Diversity, Immune Suppression, and Therapeutic Opportunities

By MedXY|Aug 5, 2026

BIA-ALCL is a heterogeneous T cell lymphoma marked by immunosuppressive tumor microenvironments that promote tumor survival and proliferation, revealing potential targets for advanced disease therapy.

Targeting NEK9 to Overcome Immunotherapy Resistance in Hepatocellular Carcinoma by Reprogramming the Tumor Microenvironment
Gastroenterologyhepatocellular carcinomaimmunotherapy

Targeting NEK9 to Overcome Immunotherapy Resistance in Hepatocellular Carcinoma by Reprogramming the Tumor Microenvironment

By MedXY|Jun 27, 2026

NEK9 upregulation in hepatocellular carcinoma promotes immune evasion by enhancing PD-L1 expression and recruiting suppressive myeloid cells. Novel NEK9 inhibitors synergize with PD-L1 blockade, remodeling the tumor microenvironment and imp

Fibrosis-Driven Activation of Schwann Cells in Pancreatic Cancer: Unraveling the Nuclear Mechanosensing Pathway
GastroenterologyfibrosisMechanosensing

Fibrosis-Driven Activation of Schwann Cells in Pancreatic Cancer: Unraveling the Nuclear Mechanosensing Pathway

By MedXY|Jun 25, 2026

Pancreatic fibrosis activates Schwann cells via nuclear mechanosensing, promoting a protumorigenic environment that enhances pancreatic cancer progression, offering novel microenvironment-targeted therapeutic insights.

Molecular and Spatial Differences in the Tumor Microenvironment of High-Grade Serous Ovarian Cancer With Short vs Long-Term Survival
newsfibroblastshigh-grade serous ovarian cancer

Molecular and Spatial Differences in the Tumor Microenvironment of High-Grade Serous Ovarian Cancer With Short vs Long-Term Survival

By MedXY|May 26, 2026

This study found that advanced high-grade serous ovarian cancers from short-term survivors had more fibroblasts and stromal invasion signals, while tumors from long-term survivors showed stronger immune pathways, suggesting the tumor microe

Tumor-Infiltrating Clonal Hematopoiesis Emerges as a Pan-Cancer Prognostic Signal in Solid Tumors
Hematology-OncologyClonal hematopoiesisoverall survival

Tumor-Infiltrating Clonal Hematopoiesis Emerges as a Pan-Cancer Prognostic Signal in Solid Tumors

By MedXY|May 9, 2026

A large whole-genome sequencing study found tumor-infiltrating clonal hematopoiesis in 18.4% of solid tumors, linked to older age, prior cytotoxic chemotherapy, and worse overall survival, with particularly strong associations in breast can

Patient-Derived Medullary Thyroid Cancer Models Capture Tumor Plasticity and Drug Resistance Beyond Genomics
newsmedullary thyroid carcinomapatient-derived models

Patient-Derived Medullary Thyroid Cancer Models Capture Tumor Plasticity and Drug Resistance Beyond Genomics

By MedXY|Apr 1, 2026

Patient-derived medullary thyroid cancer models preserved tumor heterogeneity, microenvironmental stem-like features, and variable tyrosine kinase inhibitor response, supporting more personalized preclinical testing.

Optimizing Immunotherapy in Cholangiocarcinoma: Low-Dose Chemotherapy as a Catalyst for Immune Microenvironment Remodeling
Clinical UpdatesCholangiocarcinomaimmunotherapy

Optimizing Immunotherapy in Cholangiocarcinoma: Low-Dose Chemotherapy as a Catalyst for Immune Microenvironment Remodeling

By MedXY|Mar 7, 2026

This review examines how low-dose gemcitabine and cisplatin (LDGC) synergize with anti-PD-L1 therapy in intrahepatic cholangiocarcinoma by reprogramming immunosuppressive SPP1+ macrophages and enhancing CD8+ T-cell cytotoxicity through STAT

Preoperative Pembrolizumab Plus Chemoradiotherapy (PPCT) for Locally Advanced Resectable ESCC: PALACE‑2 Phase 1/2 Results and Immune‑Microenvironment Insights
newsesophageal squamous cell carcinomaneoadjuvant immunotherapy

Preoperative Pembrolizumab Plus Chemoradiotherapy (PPCT) for Locally Advanced Resectable ESCC: PALACE‑2 Phase 1/2 Results and Immune‑Microenvironment Insights

By MedXY|Dec 1, 2025

PALACE‑2 reports that preoperative pembrolizumab combined with chemoradiotherapy produced a 43.2% pathologic complete response in resectable, locally advanced esophageal squamous cell carcinoma, with acceptable short‑term survival and a hig

Tumor Microenvironment-Responsive Mn-Based Nanoplatform Activates cGAS-STING Pathway Coupled with Metabolic Interference for Enhanced Antitumor Therapy
Allergy & ImmunologyTumor Microenvironment

Tumor Microenvironment-Responsive Mn-Based Nanoplatform Activates cGAS-STING Pathway Coupled with Metabolic Interference for Enhanced Antitumor Therapy

By MedXY|Oct 5, 2025

A novel Mn-based nanoplatform, LT@MnO@MON-HA (LMMH), responsive to tumor microenvironment triggers metabolic disruption and robust cGAS-STING activation, potentiating chemodynamic therapy and immunotherapy for improved tumor suppression.

Manganese: A Potent Catalyst Enhancing Cancer Immunotherapy
Allergy & ImmunologyCancer ImmunotherapyNanoparticles

Manganese: A Potent Catalyst Enhancing Cancer Immunotherapy

By MedXY|Oct 5, 2025

Manganese and its nanoparticles play a pivotal role in cancer immunotherapy by modulating immune pathways, reshaping the tumor microenvironment, and serving as effective adjuvants and drug carriers, offering promising avenues to overcome cu

Ask MedXY AI

Most popular

Intimate Health
Five Benefits for Women Continuing Sexual Activity After Menopause
Intimate Health
Why Some Women Have a Strong Sex Drive—And Why Men Shouldn't Worry About It
Nursing & care
How often should a couple have sex?
Intimate Health
Classic Intimacy Recommendations: How to Help Women Reach Orgasm and Enjoy Mutual Pleasure
Intimate Health
What Makes a Woman "Physiologically Addicted" Is Never Money, But These Two Relationship Qualities