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Internal MedicineJAK inhibitorsmuscle wasting

Tofacitinib Reverses Muscle Loss in Rheumatoid Arthritis: Insights from the RAMUS Trial

By MedXY|Dec 19, 2025

The RAMUS study demonstrates that the JAK inhibitor tofacitinib significantly increases lower limb muscle volume in patients with rheumatoid arthritis, offering a potential explanation for associated creatinine elevations and a new therapeu

Internal MedicineJAK inhibitorsmuscle wasting

Tofacitinib and Muscle Volume: A Potential Paradigm Shift in Managing Rheumatoid Cachexia

By MedXY|Dec 19, 2025

The RAMUS study demonstrates that tofacitinib significantly increases lower limb muscle volume in rheumatoid arthritis patients, potentially explaining associated creatinine elevations and offering a new therapeutic avenue for combating mus

rheumatoid arthritis

Latest news

Tofacitinib Reverses Muscle Loss in Rheumatoid Arthritis: Insights from the RAMUS Trial

Tofacitinib and Muscle Volume: A Potential Paradigm Shift in Managing Rheumatoid Cachexia

Unveiling Early Rheumatoid Arthritis-Associated Interstitial Lung Disease: Risk Factors and Validation of Screening Approaches in the SAIL-RA Cohort

Diagnosing and Managing Methotrexate-Induced Osteopathy in Rheumatologic Practice

Distinguishing Low-Grade MRI Inflammation in Rheumatoid Arthritis: Insights from Healthy Controls and At-Risk Populations

Dual JAK and ROCK Inhibition with CPL’116: A Promising Advance for Methotrexate-Refractory Rheumatoid Arthritis

Intermittent Fasting in Overweight and Obese Postmenopausal Women with Rheumatoid Arthritis: Insights from a Randomized Controlled Trial

Functional MRI Brain Activation as a Predictor of Response to TNF Inhibition in Rheumatoid Arthritis: Insights from the PreCePra Phase 3 Study

FDA Approves First Vagus Nerve Stimulation Device for Rheumatoid Arthritis: New Horizons for Refractory Disease

Personal and Household Pesticide Exposure Linked to Increased Risk of Rheumatoid Arthritis in Female Farm Spouses