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Persistent Plasma Protein Alterations After Long-Term Remission in Cushing’s Disease: Implications for Morbidity and Monitoring
Diabetes & EndocrinologyPlasma Proteinsapolipoproteins

Persistent Plasma Protein Alterations After Long-Term Remission in Cushing’s Disease: Implications for Morbidity and Monitoring

By MedXY|Sep 21, 2026

This study reveals that despite long-term remission in Cushing’s disease, substantial plasma protein abnormalities persist, particularly in coagulation and complement systems, potentially contributing to ongoing health risks.

Evolving Paradigms in Pediatric Hyperthyroidism: A Two-Decade Review of Management and Outcomes
Clinical UpdatesGraves' Diseasepediatric hyperthyroidism

Evolving Paradigms in Pediatric Hyperthyroidism: A Two-Decade Review of Management and Outcomes

By MedXY|Jun 27, 2026

This review synthesizes 20 years of data on pediatric hyperthyroidism, highlighting shifts toward prolonged antithyroid drug therapy, reduced definitive treatments, and rising relapse rates, underscoring the need for individualized long-ter

Long-Term Impact of Treat-to-Target Urate-Lowering Therapy on Ultrasound-Detected Crystal Depositions and Clinical Outcomes: Insights from the 5-Year NOR-Gout Study
Clinical Updatesgoutremission

Long-Term Impact of Treat-to-Target Urate-Lowering Therapy on Ultrasound-Detected Crystal Depositions and Clinical Outcomes: Insights from the 5-Year NOR-Gout Study

By MedXY|Dec 4, 2025

The 5-year NOR-Gout study demonstrates that sustained low serum urate via treat-to-target therapy leads to dissolution of crystal deposits, reduced flares, and increased remission rates, highlighting the clinical value of long-term urate co

Prediabetes Remission Without Weight Loss: Rethinking Targets to Prevent Type 2 Diabetes
Diabetes & Endocrinologydiabetes preventionprediabetes

Prediabetes Remission Without Weight Loss: Rethinking Targets to Prevent Type 2 Diabetes

By MedXY|Nov 12, 2025

A post hoc analysis of PLIS and replication in the DPP show that achieving prediabetes remission—normalization of glucose—can prevent type 2 diabetes even without net weight loss, via improved insulin sensitivity, β‑cell function and favora

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