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Dentistry

Three-Year Clinical Evaluation of Universal Adhesive Performance Using Optical Coherence Tomography

A 36-month clinical trial using optical coherence tomography (OCT) reveals superior performance of Scotchbond™ Universal Adhesive in selective enamel-etch mode for restoring cervical lesions, with lower bond failure and adhesive defects com

Oct 22, 2026
Superintelligence

Predicting Central Serous Chorioretinopathy Outcomes Using Interpretable AI-Driven OCT Biomarkers: Insights from a Multicenter Cohort Study

A multicenter study demonstrates that interpretable machine learning applied to baseline OCT biomarkers accurately predicts chronicity in central serous chorioretinopathy, facilitating early risk stratification and personalized management.

Oct 21, 2026
news

Unraveling the Complex 3D Architecture of Outer Retinal Tubulation in Bietti Crystalline Dystrophy

This study elucidates the intricate three-dimensional morphology and cellular organization of outer retinal tubulation (ORT) in Bietti crystalline dystrophy, revealing structural reorganization of residual outer retina with potential implic

Oct 10, 2026
news

Enhancing Choroidal Tumor Assessment with Ultra-Widefield Swept-Source OCT: A Comparative Analysis with Ultrasonography, SD-OCT, and MRI

Ultra-widefield swept-source OCT excels in assessing small-to-medium choroidal tumors, outperforming SD-OCT and providing detailed structural insights with noninvasive precision, though larger or complex tumors benefit from multimodal imagi

Oct 9, 2026
news

Unraveling Mid-phase Hyperfluorescent Plaques in Central Serous Chorioretinopathy: Insights from Multimodal Imaging

This study elucidates the dynamic nature and structural correlates of mid-phase hyperfluorescent plaques on ICGA in CSCR, highlighting their progression stages and OCT features that signal disease activity.

Oct 8, 2026
Infectious Diseases

Temporal Dynamics of Posterior Segment Imaging in Ocular Syphilis: Clinical Correlates and Laboratory Insights

This study elucidates distinct temporal patterns of posterior segment imaging features in ocular syphilis correlated with symptom duration and laboratory markers, enhancing diagnostic timing and clinical interpretation.

Aug 24, 2026
news

PRISM Framework: A Comprehensive Staging System for Open-Angle Glaucoma and Risk Stratification

This article presents the PRISM model, a unified glaucoma classification integrating risk profiling, structural imaging, functional testing, and disease progression to enhance diagnosis and inform treatment strategies for open-angle glaucom

Aug 11, 2026
Diabetes & Endocrinology

Hyperreflective Abnormal Areas in Middle Retinal Layers via En Face OCT: A Novel Biomarker for Diabetic Retinopathy Risk Stratification

Hyperreflective abnormalities in middle retinal layers detected by en face OCT improve diagnostic discrimination of referable diabetic retinopathy, offering a promising adjunct biomarker beyond clinical parameters.

Jul 15, 2026
Clinical Updates

Neuroretinal Layer Thinning on OCT Imaging and Hemoglobin A1c in Youth With Type 1 Diabetes: Emerging Insights and Clinical Implications

This review synthesizes evidence linking neuroretinal layer thinning observed by OCT with glycemic control and diabetic retinal disease in youth with type 1 diabetes, emphasizing early neurodegeneration preceding vascular changes and its po

Jul 2, 2026
news

Retinal Nerve Fiber Layer Thickness at 36 Weeks May Help Predict 2-Year Neurodevelopment in Very Preterm Infants

In very preterm infants, thicker retinal nerve fiber layer on OCT at 36 weeks’ postmenstrual age was associated with better motor and cognitive outcomes at 2 years, supporting retinal imaging as a potential early neurodevelopmental biomarke

Jun 8, 2026
news

Optical Coherence Tomography Features of Inactive Multifocal Choroiditis with Panuveitis and Punctate Inner Choroidopathy Lesions

OCT imaging revealed that inactive MFCPU/PIC lesions commonly show Bruch’s membrane disruption, inner retinal herniation, and focal choroidal excavation, helping distinguish them from inflammatory and infectious mimickers.

May 29, 2026Sign in to read
Superintelligence

Breaking the Hardware Barrier: How Domain-Shift AI Enables Vendor-Agnostic 3D OCT Macular Disease Detection

A multicenter study in JAMA Ophthalmology introduces a deep learning model using domain-shift technology to accurately detect macular diseases across different OCT hardware vendors, achieving high negative predictive value and establishing

Feb 27, 2026

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    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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