immunogenicity

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DR5/Ligase 3 Feedback Loop: Unlocking the Immunogenicity of Mismatch Repair-Deficient Colorectal Cancer

This study uncovers a novel DR5/Ligase 3 feedback mechanism that sustains immunogenicity and enhances immune checkpoint inhibitor response in mismatch repair-deficient colorectal cancer.

Section: GastroenterologyJul 20, 2026

Two-Dose HeV-sG-V Regimen Demonstrates Robust Neutralizing Antibody Response Against Nipah Virus in Phase 1 Trial

A Phase 1 trial confirms that the HeV-sG-V vaccine is safe and, when administered in a two-dose 100 μg regimen, induces high levels of neutralizing antibodies against both Bangladesh and Malaysia strains of the Nipah virus.

immunogenicity

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DR5/Ligase 3 Feedback Loop: Unlocking the Immunogenicity of Mismatch Repair-Deficient Colorectal Cancer

Two-Dose HeV-sG-V Regimen Demonstrates Robust Neutralizing Antibody Response Against Nipah Virus in Phase 1 Trial

Novel Type 1 and Type 3 Live Attenuated Oral Poliovirus Vaccines Show Comparable Safety, Immunogenicity, and Shedding to Sabin mOPV in First‑in‑Human Phase 1 Trial

EuTCV Vi‑CRM197 (Single‑ and Multidose) Is Non‑Inferior to Typbar TCV in Infants and Well Tolerated Across Age Groups in Kenya and Senegal

Immunogenicity and HPV Infection After One, Two, and Three Doses of Quadrivalent HPV Vaccine in Indian Girls: A Multicentre Prospective Cohort Study

A Single Shot Against Rift Valley Fever? Phase 1 ChAdOx1 RVF Trial Shows Acceptable Safety and Robust Immune Responses in Uganda

rVSVΔG‑LASV‑GPC Lassa Vaccine Shows Broad Immunogenicity and Acceptable Safety in Phase 1 Trial

Boosting Immunity Against Group B Streptococcus: Safety and Efficacy of a Novel Hexavalent Conjugate Vaccine Booster in Healthy Adults

Breakthrough in Enteric Fever Prevention: Efficacy and Safety of the Novel Salmonella Paratyphi A Vaccine CVD 1902

Evaluating the Safety and Immunogenicity of the Adjuvanted RSVPreF3 Vaccine in High-Risk Transplant Recipients: A Critical Analysis of an Interventional Cohort Study

Promising Immunogenicity and Safety of the Live-Attenuated Intranasal RSV Vaccine in Infants and Toddlers

M72/AS01E-4 Tuberculosis Vaccine: Promising Advances for HIV-Positive Populations in High-Burden Settings

Impact of Maternal Pertussis Vaccination on Infant Immune Responses: Insights from the GaPS Trial in The Gambia