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MedXY AI/MedXY News/Tag: Brain Injury
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Unveiling the Systemic Drivers of Blood-Brain Barrier Disruption in Sickle Cell Disease: Insights from Proteomic Profiling
Hematology-OncologyBrain Injurysickle cell disease

Unveiling the Systemic Drivers of Blood-Brain Barrier Disruption in Sickle Cell Disease: Insights from Proteomic Profiling

By MedXY|Sep 21, 2026

This study identifies systemic pathological pathways that mediate blood-brain barrier injury in sickle cell disease, linking BBB disruption to brain hypoxia and microstructural injury, highlighting new therapeutic targets to preserve neurol

Unveiling Metabolic Signatures: Glucose and Methionine PET Imaging in Disorders of Consciousness Post-Brain Injury
NeurologyFDG-PET
Brain Injury

Unveiling Metabolic Signatures: Glucose and Methionine PET Imaging in Disorders of Consciousness Post-Brain Injury

By MedXY|Aug 26, 2026

This exploratory longitudinal study reveals that alongside decreased glucose metabolism, elevated brainstem methionine uptake correlates with consciousness improvement in brain-injured patients, highlighting novel metabolic biomarkers for p

Acute Brain Injury in New-Onset Refractory Status Epilepticus and Etiology-Defined Status Epilepticus
Critical CarebiomarkerNORSE

Acute Brain Injury in New-Onset Refractory Status Epilepticus and Etiology-Defined Status Epilepticus

By MedXY|Jun 10, 2026

This study found that cryptogenic NORSE causes severe, rapidly rising neuroaxonal injury, measured by NfL, and that higher NfL predicts worse short-term outcome. S100B was not useful for distinguishing groups.

Plasma GFAP and NfL as Real-Time Predictors of Brain Injury and Long-Term Disability in Pediatric ECMO
Critical Carebiomarkersneurocritical care

Plasma GFAP and NfL as Real-Time Predictors of Brain Injury and Long-Term Disability in Pediatric ECMO

By MedXY|Mar 2, 2026

A prospective study demonstrates that rising levels of plasma GFAP and NfL precede neuroimaging-confirmed brain injury in children on ECMO. These biomarkers are also strongly associated with mortality and long-term functional impairment, of

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