Reevaluating RhD-Positive Whole Blood Use in Trauma Patients with Reproductive Potential: Ethical and Clinical Implications Post-Two Randomized Trials
hemolytic disease of the fetus and newbornreproductive potentialRhD-positive whole bloodtrauma resuscitationanti-D alloimmunization
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Recent randomized control trials demonstrate no survival benefit when using whole blood, typically RhD-positive, over component therapy in prehospital trauma resuscitation.
Transfusing RhD-positive whole blood to RhD-negative patients with reproductive potential poses preventable risks of anti-D alloimmunization and subsequent hemolytic disease of the fetus and newborn.
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.