Patient Perspectives on Prolactinoma in Females: Insights from the Dutch Cohort Studies

Highlight

• Fatigue and cognitive complaints are the most prevalent and burdensome symptoms among females with prolactinoma, regardless of disease control status.
• Active prolactinoma, defined by elevated prolactin levels, is associated with significantly higher anxiety, depression, and overall disease burden compared to controlled prolactinoma.
• Despite effective prolactin normalization in nearly all patients using dopamine agonists, symptom burden remains substantial, underscoring unmet therapeutic and rehabilitative needs.

Study Background