Optimizing Prognostic Accuracy in Duodenal Adenocarcinoma: Evaluating Lymph Node Staging Schemes and a Novel Nomogram

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This article critically examines three lymph node-related prognostic indicators for duodenal adenocarcinoma — positive lymph nodes (PLN), lymph node ratio (LNR), and log odds of positive lymph nodes (LODDS) — comparing their predictive performance in Western and Eastern patient cohorts. It establishes LODDS, especially in its categorical classification, as the most powerful prognostic marker and presents a novel nomogram integrating LODDS with key clinical factors for robust individualized survival prediction.

Study Background