Impact of Induction Course Number on Outcomes of Allogeneic Stem Cell Transplant with Post-Transplant Cyclophosphamide in AML
acute myeloid leukemiaallogeneic stem cell transplantationinduction chemotherapyposttransplant cyclophosphamiderelapse
Highlight
- Analysis of 677 adult AML patients undergoing allogeneic stem cell transplantation (alloHSCT) with post-transplant cyclophosphamide (PTCy) in first complete remission.
- Comparison between patients achieving CR1 after one induction chemotherapy course versus those requiring two courses.
- Similar overall survival, leukemia-free survival, and GVHD-free/relapse-free survival despite higher relapse incidence in the two-induction group.
- Findings support alloHSCT with PTCy as effective regardless of induction course number needed for remission.
Study Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.