Harnessing Genomics for Precision Prevention in Psychiatry: Opportunities and Challenges
Highlight
- Genomic testing is not currently recommended for universal screening in psychiatry due to modest predictive power and possible psychological harms.
- Rare high-impact genetic variants have value in early clinical settings for diagnosis, prognosis, and personalized management.
- Polygenic scores may aid in risk stratification within high-risk psychiatric populations when combined with non-genetic factors.
- Pharmacogenomics and genomics-informed somatic risk assessment offer important opportunities for secondary and tertiary prevention in mental illness.
Background: Burden of Psychiatric Disorders and Need for Preventive Strategies
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.