Early Pregnancy Glycemic Testing Enhances Gestational Diabetes Prediction: Insights from the GO MOMs Study
continuous glucose monitoringEarly Pregnancy ScreeningGestational diabetes mellituslarge-for-gestational-ageOral Glucose Tolerance Test
Highlight
- Early pregnancy (10-14 weeks) oral glucose tolerance test (OGTT) and continuous glucose monitoring (CGM) data improve prediction of gestational diabetes mellitus (GDM) beyond clinical factors alone.
- Adding OGTT to clinical risk factors increased the positive predictive value for GDM from 12.2% to 26.5% while maintaining a high negative predictive value (≥96%).
- Neither early pregnancy OGTT nor CGM added predictive value for large-for-gestational-age (LGA) birth weights over clinical factors.
- These findings support potential benefits of early glycemic assessment to identify women at risk for GDM and guide earlier interventions.
Study Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.