Tenecteplase Efficacy in Distal Cerebral Artery Occlusions: Insights From the Secondary Analysis of the TASTE Randomized Clinical Trial
Highlights
- Tenecteplase shows improved 90-day functional outcomes compared to alteplase in distal (M3 and beyond) middle cerebral artery occlusions.
- Distinct efficacy signals observed in distal M2 and anterior cerebral artery occlusions favor tenecteplase, though not reaching statistical significance.
- No significant differences were found in proximal M2 or posterior cerebral artery occlusions, or across ischemic core and perfusion profiles.
- Findings support expanding tenecteplase use beyond large and medium vessel occlusions to include distal cerebral artery stroke subtypes.
Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.