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Tocilizumab Reduces Major Cardiovascular Events Risk in Giant Cell Arteritis: Insights from a Nationwide French Cohort
Cardiologytocilizumabcardiovascular risk

Tocilizumab Reduces Major Cardiovascular Events Risk in Giant Cell Arteritis: Insights from a Nationwide French Cohort

By MedXY|Sep 8, 2026

A nationwide observational study reveals tocilizumab use in giant cell arteritis significantly lowers major adverse cardiovascular events compared to methotrexate, highlighting its potential cardiovascular benefits beyond inflammation contr

Interleukin 6 Receptor Blockade: A Promising Strategy for Relapse Prevention in MOG Antibody-Associated Disease
Allergy & ImmunologyInterleukin 6 receptor blockade
IVIG

Interleukin 6 Receptor Blockade: A Promising Strategy for Relapse Prevention in MOG Antibody-Associated Disease

By MedXY|Jul 16, 2026

IL-6 receptor blockade significantly reduces relapse rates in MOG antibody-associated disease, showing comparable efficacy to high-dose IVIG with a favorable safety profile, supporting its role in relapse prevention.

Interleukin 6 as a Treatment Target for Depression: A Proof-of-Concept Randomized Clinical Trial
newsdepressioninflammation

Interleukin 6 as a Treatment Target for Depression: A Proof-of-Concept Randomized Clinical Trial

By MedXY|Jun 2, 2026

A small randomized trial found that blocking IL-6 with tocilizumab showed promising, clinically meaningful trends for inflammation-related, hard-to-treat depression, especially for somatic symptoms, fatigue, anxiety, and quality of life, th

Tocilizumab Shows Promising Benefits in Glucocorticoid-Resistant Thyroid Eye Disease
Diabetes & EndocrinologyGraves' orbitopathyInterleukin-6

Tocilizumab Shows Promising Benefits in Glucocorticoid-Resistant Thyroid Eye Disease

By MedXY|May 13, 2026

In two prospective cohorts of active, glucocorticoid-resistant thyroid eye disease, tocilizumab improved eye inflammation, proptosis, diplopia, and quality of life with acceptable safety, supporting IL-6 blockade as a promising second-line

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