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Cardiology

Impact of Familial Hypercholesterolaemia on Thymic Ageing: Insights from a Large Chinese Cohort

This study reveals that familial hypercholesterolaemia accelerates thymic ageing, reducing thymic output and altering T-cell diversity; statin therapy partially preserves thymic function, suggesting integrated metabolic-immunologic manageme

Oct 27, 2026
Diabetes & Endocrinology

Pediatric Type 1 Diabetes Care Still Misses LDL Targets Despite Clear Indications for Lipid-Lowering Therapy

Registry data from 55,028 youths with type 1 diabetes show common LDL hypercholesterolemia, infrequent lipid-lowering therapy, and poor attainment of recommended LDL targets.

May 10, 2026Sign in to read
Cardiology

Timing Matters: Delayed Statin Initiation After Incidental High LDL-C Detection Significantly Increases Myocardial Infarction Risk

A large-scale cohort study demonstrates that delaying statin therapy following the incidental discovery of high LDL-C during routine health screenings leads to a progressively higher risk of myocardial infarction, emphasizing the critical i

Jan 3, 2026Sign in to read
Cardiology

Comparing the PREVENT and PCE Models for 10-Year ASCVD Risk Prediction: Insights from a Large Real-World Cohort

This review evaluates PREVENT versus PCE models for estimating 10-year ASCVD risk focusing on accuracy in patients with and without statin therapy, highlighting implications for personalized prevention.

Sep 20, 2025

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