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Higher Sodium Excretion, Measured by Multiple 24-Hour Urine Samples, Linked to Increased Type 2 Diabetes Risk
Diabetes & Endocrinologysodium intaketype 2 diabetes

Higher Sodium Excretion, Measured by Multiple 24-Hour Urine Samples, Linked to Increased Type 2 Diabetes Risk

By MedXY|Jul 28, 2026

In a prospective cohort study using multiple 24-hour urine collections, higher sodium excretion was associated with a 32% increased type 2 diabetes risk per 1,000 mg/day; potassium excretion showed no significant association.

Interaction Between SGLT2 Inhibition and Dietary Sodium: Insights from the CREDENCE Trial Post Hoc Analysis
CardiologyCanagliflozinchronic kidney disease
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Interaction Between SGLT2 Inhibition and Dietary Sodium: Insights from the CREDENCE Trial Post Hoc Analysis

By MedXY|Mar 15, 2026

This post hoc analysis of the CREDENCE trial reveals that low-normal sodium intake increases cardiovascular risk in T2D and CKD, a risk significantly mitigated by canagliflozin, while renal protection remains consistent across sodium intake

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