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Pre-pregnancy Uterine Surgery Linked to Increased Risks of Preterm Birth and Stillbirth: Insights from a Large Population Study
newspreterm birthObstetrics

Pre-pregnancy Uterine Surgery Linked to Increased Risks of Preterm Birth and Stillbirth: Insights from a Large Population Study

By MedXY|Sep 9, 2026

Uterine surgery before first pregnancy is associated with increased risks of preterm birth and stillbirth, with risk magnifying after repeated procedures, highlighting the need for careful surgical decision-making and enhanced antenatal mon

Long COVID in Pregnancy: Assessing Risks for Preterm Birth and Hypertensive Disorders
Infectious Diseasespreterm birth
hypertensive disorders

Long COVID in Pregnancy: Assessing Risks for Preterm Birth and Hypertensive Disorders

By MedXY|Aug 31, 2026

This study evaluates the impact of Long COVID on pregnancy outcomes, finding no significant risk for preterm birth but a potential association with hypertensive disorders, underscoring the need for further research.

High Versus Low Transvaginal Cerclage for Preventing Preterm Birth: Insights from the C-STICH Trial Secondary Analysis
newsC-STICH trialtransvaginal cerclage

High Versus Low Transvaginal Cerclage for Preventing Preterm Birth: Insights from the C-STICH Trial Secondary Analysis

By MedXY|Aug 22, 2026

This secondary analysis of the C-STICH trial compares pregnancy outcomes following high versus low vaginal cerclage in women at high risk of preterm birth, finding no significant difference in pregnancy loss but a modest benefit of high cer

High Versus Low Vaginal Cerclage: Effects on Pregnancy Outcomes in Women at High Risk of Preterm Birth
newsC-STICH trialtransvaginal cerclage

High Versus Low Vaginal Cerclage: Effects on Pregnancy Outcomes in Women at High Risk of Preterm Birth

By MedXY|Aug 21, 2026

This analysis of the C-STICH trial compares high and low transvaginal cerclage, revealing similar pregnancy loss rates but a modest prolongation of gestation and fewer very preterm births with high cerclage.

Antenatal Magnesium Sulfate Prior to Very Preterm Birth: Real-World Association with Improved Survival Without Cerebral Palsy
Clinical UpdatesSulfat magiêBệnh liệt não

Antenatal Magnesium Sulfate Prior to Very Preterm Birth: Real-World Association with Improved Survival Without Cerebral Palsy

By MedXY|Aug 11, 2026

Antenatal magnesium sulfate (MgSO4) use before very preterm birth significantly improves survival free of cerebral palsy and moderate-severe impairment, with evidence from randomized trials and large cohort data supporting enhanced neuropro

Spontaneous Preterm Birth as a Sentinel for Cardiovascular Mortality: Insights from a National Registry Study
Cardiologycardiovascular diseaseDịch tễ học Lâm sàng

Spontaneous Preterm Birth as a Sentinel for Cardiovascular Mortality: Insights from a National Registry Study

By MedXY|Jun 4, 2026

A large-scale Dutch cohort study reveals that women with a history of spontaneous preterm birth face a significantly elevated risk of cardiovascular mortality, with the highest risk observed in those delivering before 32 weeks of gestation.

Early Developmental Intervention Linked to Sustained Executive Function Gains in Very Preterm Children
Neurologyearly interventionExecutive Function

Early Developmental Intervention Linked to Sustained Executive Function Gains in Very Preterm Children

By MedXY|Jan 26, 2026

A secondary analysis of a randomized clinical trial reveals that parent-led enhanced developmental intervention, beginning in the NICU and spanning two years, significantly improves executive function domains—including attention, inhibition

Benzodiazepine Exposure and Adverse Pregnancy Outcomes: New Evidence from a Large-Scale Target Trial Emulation
newsBenzodiazepinesDịch tễ học Lâm sàng

Benzodiazepine Exposure and Adverse Pregnancy Outcomes: New Evidence from a Large-Scale Target Trial Emulation

By MedXY|Dec 26, 2025

A large-scale cohort study emulating randomized trials indicates that benzodiazepine use during pregnancy significantly increases the risk of abortion and preterm birth, even after accounting for competing risks and maternal factors. Risks

Increased Gestational Weight Gain and Adverse Pregnancy Outcomes After Stopping GLP‑1 Receptor Agonists Prior to or in Early Pregnancy
Diabetes & EndocrinologyGestational Diabetesgestational weight gain

Increased Gestational Weight Gain and Adverse Pregnancy Outcomes After Stopping GLP‑1 Receptor Agonists Prior to or in Early Pregnancy

By MedXY|Nov 24, 2025

In a large retrospective cohort, women who discontinued GLP‑1 receptor agonists shortly before or during early pregnancy had greater gestational weight gain and higher risks of preterm birth, gestational diabetes, and hypertensive disorders

Wildfire Smoke During Pregnancy Linked to Higher Preterm Birth Risk in the US West: ECHO Cohort Analysis Shows Intensity, Duration, and Timing Matter
newsPM2.5Pregnancy

Wildfire Smoke During Pregnancy Linked to Higher Preterm Birth Risk in the US West: ECHO Cohort Analysis Shows Intensity, Duration, and Timing Matter

By MedXY|Nov 23, 2025

A nationwide ECHO analysis found wildfire-specific PM2.5 exposure was associated with increased odds of preterm birth in the US West, with stronger effects for higher concentration, longer smoke waves, and mid-to-late pregnancy exposures.

Atosiban Did Not Improve Neonatal Outcomes for Threatened Preterm Birth at 30–34 Weeks: Results from the Multicentre APOSTEL 8 Trial
newsAtosibanpreterm birth

Atosiban Did Not Improve Neonatal Outcomes for Threatened Preterm Birth at 30–34 Weeks: Results from the Multicentre APOSTEL 8 Trial

By MedXY|Dec 15, 2025

In the APOSTEL 8 randomized trial, intravenous atosiban did not reduce a composite of perinatal mortality and severe neonatal morbidity versus placebo for threatened preterm birth at 30+0–33+6 weeks.

Nationwide Prevention Programme in Australia Associated with Lower Preterm and Early‑Term Singleton Births: National and Hospital‑Level Results
newscervical lengthpreterm birth

Nationwide Prevention Programme in Australia Associated with Lower Preterm and Early‑Term Singleton Births: National and Hospital‑Level Results

By MedXY|Nov 7, 2025

A multifaceted national preterm birth prevention programme in Australia was associated with a modest national decrease in late preterm births and, after a hospital collaborative, a substantial reduction in early‑term births in participating

Long-Term Educational Trajectories After Preterm Birth: Unraveling the Roles of Biological and Sociodemographic Factors
newseducational outcomesneurodevelopment

Long-Term Educational Trajectories After Preterm Birth: Unraveling the Roles of Biological and Sociodemographic Factors

By MedXY|Oct 6, 2025

This study reveals that although individuals born preterm face higher risks of lower educational attainment, sociodemographic factors have a greater impact on long-term educational outcomes than prematurity itself.

Aspirin for Delaying Preterm Birth in High-Risk Preterm Pre-eclampsia Pregnancies: Insights from a Multicenter Randomized Trial in Asia
Clinical UpdatesAspirinpre-eclampsia

Aspirin for Delaying Preterm Birth in High-Risk Preterm Pre-eclampsia Pregnancies: Insights from a Multicenter Randomized Trial in Asia

By MedXY|Oct 8, 2025

Early low-dose aspirin reduces early preterm birth risk and delays timing of delivery in women at high risk for preterm pre-eclampsia, with significant benefits in iatrogenic preterm births and small-for-gestational-age pregnancies.

Preterm Birth Linked to Long-Term Adult Cardiometabolic and Mental Health Risks: New U.S. Cohort Study
Cardiologycardiometabolic riskmental health

Preterm Birth Linked to Long-Term Adult Cardiometabolic and Mental Health Risks: New U.S. Cohort Study

By MedXY|Sep 30, 2025

Adults born preterm face significantly higher risks of cardiometabolic abnormalities and internalizing mental health problems by age 35, according to a new U.S. cohort study.

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