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phase 1 clinical trial

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Hematology-Oncology

Ultralow-Dose IL-10–Expressing CAR T Cells Show Promising Activity in Relapsed/Refractory DLBCL

A phase 1 trial of ultralow-dose IL-10–expressing CD19 CAR T cells in 13 patients with R/R DLBCL reported a 92.3% objective response rate with manageable safety.

Jul 24, 2026
Clinical Updates

Innovative All-Oral Therapy: Linperlisib Plus Chidamide Shows Promise in Relapsed or Refractory Cutaneous T-Cell Lymphoma

A phase 1 trial of linperlisib combined with chidamide demonstrated manageable safety and notable efficacy in relapsed/refractory CTCL, offering a potential new oral treatment option for advanced disease, especially mycosis fungoides.

Sep 3, 2025

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