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Methimazole-Associated Neutropenia Common in Pediatric Graves Disease: Chinese Cohort Study
Diabetes & EndocrinologyGraves diseasemethimazole

Methimazole-Associated Neutropenia Common in Pediatric Graves Disease: Chinese Cohort Study

By MedXY|Jul 25, 2026

A cohort of 432 children with Graves disease found 24% developed neutropenia on methimazole, mostly within the first month. TPOAb-negative status and younger age increased risk.

Unveiling Diverse Inflammatory Pathways in Residual Pediatric Asthma Exacerbations Under Mepolizumab Therapy
Allergy & Immunologyasthmainflammation

Unveiling Diverse Inflammatory Pathways in Residual Pediatric Asthma Exacerbations Under Mepolizumab Therapy

By MedXY|Oct 27, 2025

This study reveals multiple distinct molecular mechanisms, including epithelial and macrophage pathways, that contribute to residual asthma exacerbations in children treated with mepolizumab, highlighting the complexity of airway inflammati

Mitigating Risks of Donor-Derived Epstein-Barr Virus Infection in Pediatric Kidney Transplantation: Advances and Challenges
Infectious DiseasesEBVInfection Risk

Mitigating Risks of Donor-Derived Epstein-Barr Virus Infection in Pediatric Kidney Transplantation: Advances and Challenges

By MedXY|Oct 27, 2025

This article reviews recent studies on EBV transmission in pediatric kidney transplants, highlighting risk factors, monitoring strategies, and implications for reducing posttransplant lymphoproliferative disorder (PTLD).

Advances in Second-Line Antiretroviral Therapy for Children with HIV in Africa: Insights from the CHAPAS-4 Trial
Clinical Updatesantiretroviral therapyHIV

Advances in Second-Line Antiretroviral Therapy for Children with HIV in Africa: Insights from the CHAPAS-4 Trial

By MedXY|Sep 30, 2025

TAF–emtricitabine and dolutegravir-based regimens outperform standard options as second-line ART for African children with HIV, offering improved viral suppression and safety.

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