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Targeting the IL-17/NGAL/NETs/ITGA5 Axis: A Novel Strategy to Overcome Immunosuppression and Fibroblast Reprogramming in Pancreatic Cancer
This study unravels how tumour-derived NGAL induces NETs that reprogram fibroblast subtypes via ITGA5, promoting immunosuppression and tumour progression in pancreatic ductal adenocarcinoma, suggesting combinatorial therapies to enhance imm
Section: GastroenterologyJul 20, 2026
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Lower Airway Dysbiosis in NTM-Positive Bronchiectasis Is Linked to NET-Dominant Severe Phenotypes
In NTM-positive bronchiectasis, lower airway dysbiosis involving Mycobacterium and oral bacteria is linked to higher NET levels and more severe disease phenotypes, suggesting that the broader airway microbiome may shape inflammation and out