
GastroenterologyTumor MicroenvironmentNeurotensin Receptor 1
Neurotensin Receptor 1: A Key Driver of Immune Exclusion and Poor Prognosis in Colorectal Cancer
By MedXY|Sep 23, 2026
High expression of neurotensin receptor 1 (NTSR1) defines an immune-cold colorectal cancer subtype linked to worse outcomes by creating mechanical and biological barriers that exclude T-cell infiltration, highlighting a novel immunotherapeu