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Medical Management Proves Superior to Endovascular Recanalization for Symptomatic Nonacute Intracranial Artery Occlusion
Neurologyneurologystroke

Medical Management Proves Superior to Endovascular Recanalization for Symptomatic Nonacute Intracranial Artery Occlusion

By MedXY|Jan 6, 2026

A multicenter cohort study (ERNA-IAO) demonstrates that endovascular recanalization significantly increases the risk of stroke and death compared to medical treatment alone in patients with symptomatic nonacute intracranial artery occlusion

A Global Standard: Understanding the New VasCog-2-WSO Criteria for Vascular Dementia
Neurologyneurologyvascular dementia

A Global Standard: Understanding the New VasCog-2-WSO Criteria for Vascular Dementia

By MedXY|Jan 2, 2026

Experts have released the VasCog-2-WSO criteria, an updated international standard for diagnosing vascular cognitive impairment and dementia. This revision introduces a preclinical stage and incorporates modern neuroimaging and fluid biomar

The Smart Thermostat for the Brain: How Adaptive DBS is Redefining Parkinson’s Treatment
Neurologymedical innovationneurology

The Smart Thermostat for the Brain: How Adaptive DBS is Redefining Parkinson’s Treatment

By MedXY|Jan 2, 2026

A groundbreaking clinical trial reveals that adaptive deep brain stimulation (aDBS) provides a safer, more efficient, and personalized way to manage Parkinson’s disease symptoms by responding to real-time brain activity.

Candesartan 16 mg Emerges as a Robust, Evidence-Based Option for Migraine Prophylaxis
NeurologyCandesartanMigraine

Candesartan 16 mg Emerges as a Robust, Evidence-Based Option for Migraine Prophylaxis

By MedXY|Dec 23, 2025

A Phase 2 triple-blind trial confirms that 16 mg of candesartan daily significantly reduces monthly migraine days compared to placebo, offering a well-tolerated oral alternative for patients with episodic migraine.

The SEIZURE Score Faces Global Challenges: International Validation Highlights Geographic Disparities in Predicting Encephalitis Seizures
Infectious Diseasesneurology

The SEIZURE Score Faces Global Challenges: International Validation Highlights Geographic Disparities in Predicting Encephalitis Seizures

By MedXY|Dec 18, 2025

An international evaluation of the SEIZURE score reveals limited global predictive power for acute seizures in encephalitis. While the tool performs well in Western Europe, particularly Portugal, its utility elsewhere is hampered by etiolog

Your Nose Knows: How Smell Loss Signals More Than a Cold — Links to 139 Diseases and What to Do About It
Neurologyneurologyolfaction

Your Nose Knows: How Smell Loss Signals More Than a Cold — Links to 139 Diseases and What to Do About It

By MedXY|Dec 13, 2025

A large prospective study links smell disturbances to at least 139 conditions. Olfactory loss can be an early sign of neurological, ENT, metabolic, or systemic disease — and a practical, underused screening tool clinicians can adopt.

Long-Term Seizure Outcomes and Epilepsy Risk in Anti-LGI1 Encephalitis: Insights from a Multicenter Cohort Study
Neurologyimmunotherapyneurology

Long-Term Seizure Outcomes and Epilepsy Risk in Anti-LGI1 Encephalitis: Insights from a Multicenter Cohort Study

By MedXY|Oct 23, 2025

This study assesses seizure remission and epilepsy risk in 236 anti-LGI1 encephalitis patients, highlighting immunotherapy’s role in seizure control and identifying biomarkers linked to persistent cognitive impairment and long-term ou

Early Intravenous Immunoglobulin Therapy Improves Long-Term Outcomes in Anti-IgLON5 Disease
NeurologyAutoimmune encephalopathyimmunotherapy

Early Intravenous Immunoglobulin Therapy Improves Long-Term Outcomes in Anti-IgLON5 Disease

By MedXY|Oct 22, 2025

This retrospective multicenter study found that early intravenous immunoglobulin treatment in anti-IgLON5 disease is linked to reduced disability and mortality, highlighting a promising immunotherapeutic strategy for this rare autoimmune en

Influenza-Associated Acute Necrotizing Encephalopathy in US Children
Clinical Updatesinfluenzaneurology

Influenza-Associated Acute Necrotizing Encephalopathy in US Children

By MedXY|Sep 30, 2025

A multicenter US study highlights the devastating burden of influenza-associated acute necrotizing encephalopathy in children, with high mortality and disability rates despite aggressive therapy, underscoring the urgent need for prevention

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