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Early Life Vascular Risk and Midlife Markers of Brain Aging: Insights from Longitudinal Neuroimaging and Cognitive Trajectory Studies
Clinical Updatesmidlife brain agingNeuroimaging Biomarkers

Early Life Vascular Risk and Midlife Markers of Brain Aging: Insights from Longitudinal Neuroimaging and Cognitive Trajectory Studies

By MedXY|Sep 17, 2026

This review synthesizes longitudinal evidence linking early adulthood vascular risks, particularly elevated systolic blood pressure and smoking, to midlife cognitive decline and brain structural alterations. It highlights critical intervent

Harnessing Effective Connectivity Between Cerebellum and Fronto-Temporal Regions for Objective Major Depressive Disorder Diagnosis: Insights From a Multi-Site fMRI Study
NeurologyfMRImajor depressive disorder

Harnessing Effective Connectivity Between Cerebellum and Fronto-Temporal Regions for Objective Major Depressive Disorder Diagnosis: Insights From a Multi-Site fMRI Study

By MedXY|Oct 30, 2025

A multi-site fMRI study demonstrates that effective connectivity patterns between the cerebellum and fronto-temporal areas accurately classify major depressive disorder with over 94% accuracy, offering a promising neuroimaging biomarker to

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