mitapivat

Targeting S-Nitrosylated PKM2: A Novel Therapeutic Frontier in Cardiac Fibrosis and Mitochondrial Dynamics

Recent evidence identifies S-nitrosylation of Pyruvate Kinase M2 (PKM2) as a specific driver of cardiac fibrosis, suggesting that activating PKM2 with drugs like mitapivat could provide a long-sought therapeutic approach for heart failure p

Mitapivat Offers New Hope for Adults with Non-Transfusion-Dependent α- and β-Thalassaemia: Results from the Phase 3 ENERGIZE Trial