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Decoding Steatohepatitic Hepatocellular Carcinoma: Multi-Omics Insights and Emerging Diagnostic-Therapeutic Pathways
Gastroenterologytherapeuticsliver cancer

Decoding Steatohepatitic Hepatocellular Carcinoma: Multi-Omics Insights and Emerging Diagnostic-Therapeutic Pathways

By MedXY|Sep 27, 2026

This study integrates multi-omics data to characterize steatohepatitic hepatocellular carcinoma (SH-HCC), establishing robust diagnostic models and identifying FABP4 as a promising therapeutic target, with implications for personalized mana

Dynamic Gut Microbiome Changes Enhance Immunotherapy Outcomes in Advanced Liver Cancer
Gastroenterologyimmune checkpoint inhibitorsliver cancer

Dynamic Gut Microbiome Changes Enhance Immunotherapy Outcomes in Advanced Liver Cancer

By MedXY|Sep 21, 2026

This longitudinal study reveals that gut microbiome remodeling during immune checkpoint inhibitor therapy in advanced liver cancer patients predicts clinical benefit, improving biomarker accuracy and survival stratification.

Mapping Liver Cancer’s Hidden Frontiers: NCACC Uncovers Rare cIgG+ Epithelial Cells Driving Tumor Invasion
Gastroenterologyliver cancerRare malignant cells

Mapping Liver Cancer’s Hidden Frontiers: NCACC Uncovers Rare cIgG+ Epithelial Cells Driving Tumor Invasion

By MedXY|Sep 15, 2026

NCACC technology identifies rare cIgG+ epithelial cells at liver cancer invasive fronts, revealing a STAT1-dependent signaling axis promoting aggressiveness and offering new therapeutic targets in liver cancer.

Long-term Risk of Hepatocellular Carcinoma After Clearance of Hepatitis B Surface Antigen
Gastroenterologychronic hepatitis BHBsAg seroclearance

Long-term Risk of Hepatocellular Carcinoma After Clearance of Hepatitis B Surface Antigen

By MedXY|Jul 14, 2026

This study evaluates the long-term incidence of liver cancer in chronic hepatitis B patients who clear hepatitis B surface antigen, finding significantly reduced cancer risk in younger patients without cirrhosis.

Stratifying Risk in Incidentally Detected Splenomegaly: Quantitative Thresholds for Hematologic and Hepatic Surveillance
Clinical Updatescirrhosisliver cancer

Stratifying Risk in Incidentally Detected Splenomegaly: Quantitative Thresholds for Hematologic and Hepatic Surveillance

By MedXY|Mar 22, 2026

This review synthesizes large-scale cohort data defining specific spleen length and volume thresholds that significantly increase the 5-year absolute risk of hematologic cancers and chronic liver disease.

From Silent Struggles to Serious Threats: Understanding Your Liver’s Journey from Hepatitis to Cancer
Gastroenterologyhepatitis Bliver cancer

From Silent Struggles to Serious Threats: Understanding Your Liver’s Journey from Hepatitis to Cancer

By MedXY|Oct 6, 2025

Explore how subtle liver symptoms can signal serious illness, the progression from hepatitis to liver cancer, and effective habits to protect your liver health.

Socioeconomic Disparities in Intrahepatic Cholangiocarcinoma in Sweden: Incidence, Treatment, and Survival in a Universal Healthcare Context
Oncologyintrahepatic cholangiocarcinomaliver cancer

Socioeconomic Disparities in Intrahepatic Cholangiocarcinoma in Sweden: Incidence, Treatment, and Survival in a Universal Healthcare Context

By MedXY|Oct 4, 2025

A nationwide Swedish study reveals significant socioeconomic disparities in intrahepatic cholangiocarcinoma incidence, treatment access, and survival despite universal healthcare coverage, underscoring persistent health inequities linked to

Obesity-Linked Liver Cancer: A Preventable Crisis on the Rise
Medical Newsliver cancerMASLD

Obesity-Linked Liver Cancer: A Preventable Crisis on the Rise

By MedXY|Sep 30, 2025

Over 60% of liver cancer cases are preventable, yet rising obesity and metabolic dysfunction threaten progress. The Lancet Commission outlines urgent strategies to curb a projected doubling of global liver cancer burden by 2050.

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