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Left Atrial Appendage Closure

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Evaluating Left Atrial Appendage Closure Versus Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation: An Updated Meta-Analysis
Cardiologyatrial fibrillationbleeding risk

Evaluating Left Atrial Appendage Closure Versus Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation: An Updated Meta-Analysis

By MedXY|Oct 3, 2026

This meta-analysis consolidates data from six RCTs comparing left atrial appendage closure (LAAC) to oral anticoagulation for stroke prevention in atrial fibrillation, highlighting reduced bleeding with LAAC but increased ischemic stroke ri

DOACs After Left Atrial Appendage Closure: Enhancing Safety Without Compromising Efficacy in the ANDES Trial
CardiologyCardiology
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DAPT

DOACs After Left Atrial Appendage Closure: Enhancing Safety Without Compromising Efficacy in the ANDES Trial

By MedXY|Jan 18, 2026

The ANDES randomized trial demonstrates that 60-day DOAC therapy post-LAAC significantly reduces bleeding events compared to DAPT, while maintaining comparable rates of device-related thrombosis, suggesting a superior safety profile for sho

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