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This study reveals that the severity of hypercortisolism in adrenocortical carcinoma patients with Cushing’s syndrome correlates with higher metastatic risk and worse survival outcomes, highlighting its role as a marker of tumor aggressiven
Cushing’s syndrome in older adults requires a tailored diagnostic approach and individualized management that prioritizes functional status and quality of life over chronological age, accounting for atypical presentations and comorbidities.
This international real-world study demonstrates that osilodrostat effectively controls hypercortisolism in adrenal Cushing syndrome, with improved blood pressure and body weight, and highlights better response in patients previously treate