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This study reveals that CLDN18.2 acquired by CD8+ T cells through trogocytosis impairs their glucose metabolism and cytotoxic function, promoting pancreatic cancer progression and systemic immune senescence. Targeting this axis may enhance
This study demonstrates that initiation of elexacaftor/tezacaftor/ivacaftor (ETI) therapy in children and adolescents with cystic fibrosis improves continuous glucose monitoring (CGM) metrics, correlating with better clinical outcomes.
Acute mild cold exposure with shivering significantly reduces 24-hour glucose levels and improves glycemic profiles in individuals with type 2 diabetes, but not in prediabetic subjects, suggesting a potential non-pharmacological interventio
This review synthesizes findings on how periventricular white matter hyperintensities (PWMHs) drive cognitive impairment in Aβ-negative individuals through distinct metabolic mediation and direct structural pathways, highlighting the clinic
Selenium supplementation at 200 µg/d may reduce fasting plasma glucose and newborn hyperbilirubinemia risk in gestational diabetes without significantly altering lipid profiles, highlighting potential but limited benefits requiring further
A groundbreaking Nature study reveals how glioblastoma reprograms glucose metabolism, exploiting environmental serine to accelerate growth and resist treatment, offering new metabolic targets for personalized therapies.
This study compares the effects of the Mediterranean diet and the Australian Guide to Healthy Eating (AGHE) on body composition and glucose metabolism, revealing significant benefits of the Mediterranean diet.
