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MedXY AI/MedXY News/Tag: Epigenetic aging
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Epigenetic aging

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Reversing Epigenetic Aging in Psoriasis: The Impact of Tildrakizumab over 52 Weeks
DermatologyIL-23 inhibitiontildrakizumab

Reversing Epigenetic Aging in Psoriasis: The Impact of Tildrakizumab over 52 Weeks

By MedXY|Aug 26, 2026

This study demonstrates that tildrakizumab, an IL-23 inhibitor, partially reverses accelerated epigenetic aging in psoriasis patients, highlighting a novel aspect of biologic therapy beyond skin inflammation control.

Mosaic Loss of Y Chromosome Links to Pulmonary Decline, Emphysema, and Accelerated Epigenetic Aging in Men: A Comprehensive Review
Clinical UpdatesCOPDemphysema

Mosaic Loss of Y Chromosome Links to Pulmonary Decline, Emphysema, and Accelerated Epigenetic Aging in Men: A Comprehensive Review

By MedXY|Jul 15, 2026

Mosaic loss of Y chromosome (mLOY) in men is strongly associated with diminished lung function, increased emphysema severity, and faster epigenetic aging, positioning mLOY as a novel biomarker for respiratory aging and COPD risk in males.

Accelerated Epigenetic Aging in HIV: Insights from a Systematic Review
HIV/AIDSantiretroviral therapyEpigenetic aging

Accelerated Epigenetic Aging in HIV: Insights from a Systematic Review

By MedXY|Oct 31, 2025

Systematic review evidence supports accelerated epigenetic aging in people living with HIV compared to uninfected individuals, highlighting the need for further research considering antiretroviral therapy and confounding factors.

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