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Targeting Leukemia Stem Cells in Unfit Acute Myeloid Leukemia with a CD70-Directed Third Agent: Promise and Caveats from the ELEVATE Trial
Clinical Updatesacute myeloid leukemiaazacitidine

Targeting Leukemia Stem Cells in Unfit Acute Myeloid Leukemia with a CD70-Directed Third Agent: Promise and Caveats from the ELEVATE Trial

By MedXY|Oct 6, 2026

This review synthesizes evidence from the ELEVATE trial on adding cusatuzumab, a CD70-targeting antibody, to venetoclax with or without azacitidine in unfit AML patients, highlighting therapeutic potential, safety concerns, and translationa

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