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Diabetes & Endocrinology

Metabolic Status Influences Bone Response to Active Vitamin D in Prediabetes: Insights from the DPVD Trial

Metabolic status, reflected by glycemic trajectories, significantly modifies the skeletal response to active vitamin D analog eldecalcitol, with greater BMD improvements observed in individuals regressing from prediabetes to normoglycemia.

Oct 4, 2026
Diabetes & Endocrinology

Evaluating the Impact of Parathyroidectomy and Bisphosphonate Therapy on Bone Mineral Density: Insights from a Multi-Institutional Study

This study assesses how often parathyroidectomy yields clinically meaningful improvements in bone mineral density, with or without adjuvant bisphosphonate treatment in patients with primary hyperparathyroidism.

Sep 28, 2026Sign in to read
Neurology

High-Intensity Resistance Training Improves Lower Limb Strength More Than Low-Moderate Intensity in Older Adults

A systematic review and meta-analysis of 18 RCTs found that high-intensity resistance training significantly improved leg press and extension strength in adults aged 50+ compared to low-moderate intensity, with similar effects on bone density and no significant difference in fall incidence or adverse events.

Jul 26, 2026
Diabetes & Endocrinology

Impact of Constitutively Active TSH Receptor Mutations on Craniofacial and Bone Morphology in Hyperthyroid Mouse Models

This study demonstrates that hyperthyroidism driven by constitutively active TSH receptor mutations alters craniofacial structure and bone mineral density in mice, offering insights into thyroid hormone’s role in skeletal development.

Jun 24, 2026
Clinical Updates

Optimizing Anabolic Therapy: A Comparative Analysis of 3-Month vs. 12-Month Romosozumab Regimens in Postmenopausal Osteoporosis

This review analyzes the LIDA trial findings, demonstrating that an abbreviated 3-month romosozumab course followed by denosumab is non-inferior to the standard 12-month regimen in increasing total hip bone mineral density, potentially redu

Mar 10, 2026
Clinical Updates

Abbreviated Romosozumab Regimens in Postmenopausal Osteoporosis: A Review of the LIDA Trial and the Shift Toward Precision Anabolic Dosing

This review evaluates the LIDA trial’s findings that 3 months of romosozumab followed by denosumab is non-inferior to 12 months of romosozumab, offering a cost-effective strategy to mitigate long-term side effects.

Mar 9, 2026
Diabetes & Endocrinology

Short-Course Romosozumab Followed by Denosumab Is Non-Inferior to Standard 12-Month Regimen for Postmenopausal Osteoporosis

The LIDA trial demonstrates that a 3-month abbreviated course of romosozumab followed by denosumab is non-inferior to the standard 12-month regimen in increasing total hip bone mineral density, potentially reducing treatment costs and injec

Feb 24, 2026
Family Medicine & Nutrition

Impact of Mediterranean Diet and Physical Activity on Bone Health in Older Adults: Insights from the PREDIMED-Plus Trial

A 3-year randomized trial reveals that a weight-loss Mediterranean diet combined with physical activity helps prevent bone mineral density decline in older women with metabolic syndrome.

Sep 18, 2025

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