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DKK2 Inhibition: A Novel Neurovascular Strategy to Salvage the Ischaemic Penumbra and Protect the Blood-Brain Barrier

By MedXY|Jan 2, 2026

New research published in the European Heart Journal identifies Dickkopf-related protein 2 (DKK2) as a primary driver of neurovascular injury post-stroke. By suppressing Wnt signalling, DKK2 exacerbates neuronal death and blood-brain barrie

Neurologyblood–brain barrierMucopolysaccharidosis II

blood–brain barrier

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DKK2 Inhibition: A Novel Neurovascular Strategy to Salvage the Ischaemic Penumbra and Protect the Blood-Brain Barrier

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