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Unraveling the Neurobiological Pathways Linking Childhood Trauma to Bipolar Disorder: Insights from the ENIGMA Consortium

By MedXY|Aug 12, 2026

An international study reveals that childhood trauma’s association with bipolar disorder is partially mediated by brain morphology changes, particularly in hippocampal volume and frontal cortical thickness.

Differential Brain Lithium Dynamics in Bipolar Disorder: Insights from 7Li MRI Comparing Once- vs Twice-Daily Dosing Regimens

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bipolar disorder

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Unraveling the Neurobiological Pathways Linking Childhood Trauma to Bipolar Disorder: Insights from the ENIGMA Consortium

Differential Brain Lithium Dynamics in Bipolar Disorder: Insights from 7Li MRI Comparing Once- vs Twice-Daily Dosing Regimens

Serial Dependence in Working Memory Distinguishes Schizophrenia From Bipolar Disorder With Psychosis

Transdiagnostic Prediction Model Accurately Identifies Risk for Psychotic and Bipolar Disorders in Clinical Practice

Metformin Modestly Reduces Antipsychotic-Associated Weight Gain in Youth with Bipolar Spectrum Disorders — Large Pragmatic Trial Supports Consideration in Practice

Lithium’s Role in Reducing Suicidal Ideation and Behaviors: An Updated Meta-Analysis of Randomized Controlled Trials