Alzheimer's disease

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Rapamycin for Alzheimer’s Prevention in APOE4 Carriers: Restoring Brain Metabolism and Vascular Health

Rapamycin shows promise in preventing Alzheimer’s disease in APOE4 carriers by improving brain mitochondrial function, synaptic activity, and vascular health, highlighting a potential genotype-targeted early intervention for this high-risk

Section: NeurologyOct 21, 2025

Lifetime Walking Intensity and Duration Reduce Amyloid-β Accumulation in Alzheimer’s Disease: Insights from a Korean Longitudinal Cohort

A 4-year longitudinal study reveals that long-duration, high-intensity lifetime walking is associated with reduced amyloid-β accumulation in older adults, suggesting a neuroprotective effect when initiated early in life.

Alzheimer's disease

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Rapamycin for Alzheimer’s Prevention in APOE4 Carriers: Restoring Brain Metabolism and Vascular Health

Lifetime Walking Intensity and Duration Reduce Amyloid-β Accumulation in Alzheimer’s Disease: Insights from a Korean Longitudinal Cohort

Moderate-to-Vigorous Physical Activity, p-tau181, and Cognition in Older Adults with Memory Complaints: Insights from the MAPT Study

Blood Biomarkers of Alzheimer’s Disease Predict Long-Term Muscle Strength Decline in Older Adults

Advances in Alzheimer’s Diagnosis: A Comprehensive Review of CSF and Blood Biomarkers

Assessing the Role of Kidney Function in Alzheimer’s Disease Blood Biomarker Interpretation and Amyloid-β Positivity Prediction

Brexpiprazole in Alzheimer’s Disease-Related Agitation: Modest Gains Amidst Safety Uncertainties

Alzheimer’s Disease: Navigating Controversies and Shaping Future Strategies

Clinically Meaningful Changes in Cognitive and Functional Measures Early in Alzheimer’s Disease: Insights from Population-Based Cohorts

Promising Links Between Diabetes Medications and Alzheimer’s Disease Risk Reduction

Anti-Inflammatory Diet and Alzheimer’s Disease Mortality: Insights from a National Cohort Study

Genotype-Specific Metabolic Insights and Mediterranean Diet Impact on Dementia Risk and Cognitive Health

Precision Nutrition: Can the Mediterranean Diet Reduce Alzheimer’s Risk in APOE4 Carriers?

Unraveling the Gut–Brain Connection: Tau Propagation via the Vagus Nerve in Alzheimer’s Disease

FDA Approves Subcutaneous Lecanemab for Maintenance Treatment in Early Alzheimer’s Disease: A Step Toward More Accessible Care

Therapeutic Potential of 40 Hz Light Stimulation in Alzheimer’s Disease: Mechanisms, Modalities, and Clinical Insights

Obicetrapib Shows Promise in Slowing Alzheimer’s Disease Progression Through Lipid Modulation

Lithium Orotate as a Novel Therapeutic Avenue for Alzheimer’s Disease: Insights from the Latest Nature Study

Advancing Alzheimer’s Risk Prediction: Multi-Ancestry Polygenic Risk Scores in Hispanic Populations