Revolutionizing Cancer Therapy: Synergistic Action of Two Natural Bacteria in Complete Tumor Eradication

Highlights

• AUN, a combination of two natural bacteria, achieves complete tumor clearance in mouse and human cancer models—even in severely immunocompromised hosts.
• This bacterial therapy induces selective thrombosis and necrosis within tumors, independent of host immune cells.
• Structural transformation of tumor-resident bacteria and dramatic microbiome shifts underlie the potent, targeted antitumor effects.
• AUN demonstrates high biosafety, minimal side effects, and potential applicability across diverse cancer types.

Study Background and Disease Burden